Publications by authors named "Jonathan Rosa"

Article Synopsis
  • - The study evaluated a new hybrid compound derived from oxadiazol-4-methoxynaphthalene for its potential to inhibit a specific virus and clinical isolates, alongside its interaction with anti-tuberculosis drugs.
  • - Researchers determined the minimal inhibitory concentration, conducted time kill curve assays, and assessed pharmacokinetics and cytotoxicity to understand the effectiveness and safety of the compound.
  • - The findings suggest that the newly synthesized molecule shows promising anti-viral activity with low toxicity, making it a candidate for further development as an anti-TB drug.
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Streams are vulnerable to anthropogenic impacts, such as changes in land use, which reflect on water quality and can be evaluated by abiotic variables. In this context, the aims were to compare the abiotic values recorded in streams of different land use categories with the limits established by National legislation, and to analyze changes in abiotic variables in response to different land use impacts. Thus, 17 streams located in southern Brazil were sampled and grouped into urban, rural, and protected areas (PA) categories.

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The contamination of aquatic environments has increased over time, affecting environmental integrity and human health. Herbicides represent a source of this contamination, and among the most commercialized are the triazines and glyphosate. In contrast, there are natural herbicides, which are less harmful to the environment.

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