Publications by authors named "Jonathan R Slotkin"

Article Synopsis
  • The study explores the impact of revision surgery on patient-reported outcomes (PROs) following initial surgeries for grade 1 spondylolisthesis, comparing decompression-only and decompression plus fusion (D+F) treatments.
  • Data was collected from over 600 patients, revealing that 13.3% of decompression-only patients and 9.8% of D+F patients required revision surgery within 5 years, with revision patients reporting worse outcomes.
  • The findings indicate that while revision surgery affects PROs adversely, patients undergoing D+F see a more significant decline in their reported outcomes compared to those who only had decompression surgery.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to explore the long-term effects of body mass index (BMI) on surgical outcomes in patients with low-grade lumbar spondylolisthesis, specifically comparing obese (BMI ≥ 35) and nonobese (BMI < 35) patients.
  • Among 608 patients studied, those with a BMI ≥ 35 were generally younger, reported more severe pain and disability at baseline, and had a higher likelihood of requiring fusion surgery compared to their nonobese counterparts.
  • Five years after surgery, no significant differences were found in readmission rates or reoperation rates between the BMI groups, although higher BMI was linked to lower chances of achieving important clinical improvements post-surgery.
View Article and Find Full Text PDF

Objective: Depression and anxiety are associated with poor outcomes following spine surgery. However, the influence of these conditions on achieving a minimal clinically important difference (MCID) following lumbar spine surgery, as well as the potential compounding effects of comorbid depression and anxiety, is not well understood. This study explores the impact of comorbid depression and anxiety on long-term clinical outcomes following surgical treatment for degenerative lumbar spondylolisthesis.

View Article and Find Full Text PDF

Objective: Lumbar decompression and/or fusion surgery is a common operation for symptomatic lumbar spondylolisthesis refractory to conservative management. Multiyear follow-up of patient outcomes can be difficult to obtain but allows for identification of preoperative patient characteristics associated with durable pain relief, improved functional outcome, and higher patient satisfaction.

Methods: A query of the Quality Outcomes Database (QOD) low-grade spondylolisthesis module for patients who underwent surgery for grade 1 lumbar spondylolisthesis (from July 2014 to June 2016 at the 12 highest-enrolling sites) was used to identify patient satisfaction, as measured with the North American Spine Society (NASS) questionnaire, which uses a scale of 1-4.

View Article and Find Full Text PDF

Objective: Posterior lumbar interbody fusion (PLIF) and/or transforaminal lumbar interbody fusion (TLIF), referred to as "PLIF/TLIF," is a commonly performed operation for lumbar spondylolisthesis. Its long-term cost-effectiveness has not been well described. The aim of this study was to determine the 5-year cost-effectiveness of PLIF/TLIF for grade 1 degenerative lumbar spondylolisthesis using prospective data collected from the multicenter Quality Outcomes Database (QOD).

View Article and Find Full Text PDF
Article Synopsis
  • This study is a retrospective analysis of data collected from patients who underwent surgery for low grade spondylolisthesis, aiming to identify factors that predict delayed improvement post-surgery.
  • Among the 436 patients included, most experienced quick clinical enhancements, but about 21.4% showed delayed recovery, reaching the minimal clinically important difference (MCID) at 12 months rather than 3 months.
  • Key factors linked to this delayed improvement were poorer pre-surgery walking ability, better initial pain scores, and worse leg pain scores at the 3-month mark.*
View Article and Find Full Text PDF

Objective: Deficiency in patient education has been correlated with increased disease-related morbidity and decreased access to care. However, the associations between educational level, preoperative disease severity, and postoperative outcomes in patients with lumbar spondylolisthesis have yet to be explored.

Methods: The spondylolisthesis dataset of the Quality Outcomes Database (QOD)-a cohort with prospectively collected data by the SpineCORe study team of the 12 highest enrolling sites with an 81% follow-up at 5 years -was utilized and stratified for educational level.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare outcomes between two surgical procedures—posterior foraminotomy and anterior cervical discectomy and fusion (ACDF)—for patients with cervical radiculopathy, focusing on both clinical results and patient-reported outcomes (PROs).
  • Researchers analyzed data from 7,805 patients, matching 216 who had posterior foraminotomy to 1,080 who had ACDF based on 29 variables.
  • Results showed that while both procedures were similar in PROs, ACDF had higher patient satisfaction, shorter hospital stays were associated with posterior foraminotomy, and it also faced higher reoperation rates within a year.
View Article and Find Full Text PDF

Objective: Cervical spondylotic myelopathy (CSM) can cause significant difficulty with driving and a subsequent reduction in an individual's quality of life due to neurological deterioration. The positive impact of surgery on postoperative patient-reported driving capabilities has been seldom explored.

Methods: The CSM module of the Quality Outcomes Database was utilized.

View Article and Find Full Text PDF

Objective: Diabetes mellitus (DM) is a known risk factor for postsurgical and systemic complications after lumbar spinal surgery. Smaller studies have also demonstrated diminished improvements in patient-reported outcomes (PROs), with increased reoperation and readmission rates after lumbar surgery in patients with DM. The authors aimed to examine longer-term PROs in patients with DM undergoing lumbar decompression and/or arthrodesis for degenerative pathology.

View Article and Find Full Text PDF

Objective: Spondylolisthesis is a common operative disease in the United States, but robust predictive models for patient outcomes remain limited. The development of models that accurately predict postoperative outcomes would be useful to help identify patients at risk of complicated postoperative courses and determine appropriate healthcare and resource utilization for patients. As such, the purpose of this study was to develop k-nearest neighbors (KNN) classification algorithms to identify patients at increased risk for extended hospital length of stay (LOS) following neurosurgical intervention for spondylolisthesis.

View Article and Find Full Text PDF

Objective: The Quality Outcomes Database (QOD) was established in 2012 by the NeuroPoint Alliance, a nonprofit organization supported by the American Association of Neurological Surgeons. Currently, the QOD has launched six different modules to cover a broad spectrum of neurosurgical practice-namely lumbar spine surgery, cervical spine surgery, brain tumor, stereotactic radiosurgery (SRS), functional neurosurgery for Parkinson's disease, and cerebrovascular surgery. This investigation aims to summarize research efforts and evidence yielded through QOD research endeavors.

View Article and Find Full Text PDF

Study Design: Prospective observational study, level of evidence 1 for prognostic investigations.

Objectives: To evaluate the prevalence of sleep impairment and predictors of improved sleep quality 24 months postoperatively in cervical spondylotic myelopathy (CSM) using the quality outcomes database.

Summary Of Background Data: Sleep disturbances are a common yet understudied symptom in CSM.

View Article and Find Full Text PDF

Objective: Patient-reported outcomes (PROs) have become the standard means to measure surgical outcomes. Insurers and policy makers are also increasingly utilizing PROs to assess the value of care and measure different aspects of a patient's condition. For cervical myelopathy, it is currently unclear which outcome measure best reflects patient satisfaction.

View Article and Find Full Text PDF

Objective: Return to work (RTW) is an important surgical outcome for patients who are employed, yet a significant number of patients with cervical spondylotic myelopathy (CSM) who are employed undergo cervical spine surgery and fail to RTW. In this study, the authors investigated factors associated with failure to RTW in the CSM population who underwent cervical spine surgery and who were considered to have a good surgical outcome yet failed to RTW.

Methods: This study retrospectively analyzed prospectively collected data from the cervical myelopathy module of a national spine registry, the Quality Outcomes Database.

View Article and Find Full Text PDF
Article Synopsis
  • This study assesses the use of a new mineral-organic bone adhesive (Tetranite) compared to traditional titanium plates and screws (TPS) for fixing cranial bone flaps, highlighting potential complications of the latter.
  • In tests using human cadaver skulls, Tetranite-fixated bone flaps demonstrated significantly better stiffness and strength under stress than those using TPS, closely matching the properties of native skulls.
  • The findings suggest that Tetranite could provide a safer and more effective alternative for cranial fixation, as it reduced deflection and resistance to simulated cerebrospinal fluid leakage.
View Article and Find Full Text PDF

Objective: Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) has been used to treat degenerative lumbar spondylolisthesis and is associated with expedited recovery, reduced operative blood loss, and shorter hospitalizations compared to those with traditional open TLIF. However, the impact of MI-TLIF on long-term patient-reported outcomes (PROs) is less clear. Here, the authors compare the outcomes of MI-TLIF to those of traditional open TLIF for grade I degenerative lumbar spondylolisthesis at 60 months postoperatively.

View Article and Find Full Text PDF

Thoracic disc herniations can cause radiculopathy and myelopathy from neural compression. Surgical resection may require complex, morbid approaches. To avoid spinal cord retraction, wide exposures requiring extensive tissue, muscle, and bony disruption are needed, which may require instrumentation.

View Article and Find Full Text PDF

Objective: Prior studies have revealed that a body mass index (BMI) ≥ 30 is associated with worse outcomes following surgical intervention in grade 1 lumbar spondylolisthesis. Using a machine learning approach, this study aimed to leverage the prospective Quality Outcomes Database (QOD) to identify a BMI threshold for patients undergoing surgical intervention for grade 1 lumbar spondylolisthesis and thus reliably identify optimal surgical candidates among obese patients.

Methods: Patients with grade 1 lumbar spondylolisthesis and preoperative BMI ≥ 30 from the prospectively collected QOD lumbar spondylolisthesis module were included in this study.

View Article and Find Full Text PDF

Background: It remains unclear how type of insurance coverage affects long-term, spine-specific patient-reported outcomes (PROs). This study sought to elucidate the impact of insurance on clinical outcomes after lumbar spondylolisthesis surgery.

Methods: The prospective Quality Outcomes Database registry was queried for patients with grade 1 degenerative lumbar spondylolisthesis who underwent single-segment surgery.

View Article and Find Full Text PDF

Objective: Cervical spondylotic myelopathy (CSM) is a common progressive spine disorder affecting predominantly middle-aged and elderly populations. With increasing life expectancy, the incidence of CSM is expected to rise further. The outcomes of elderly patients undergoing CSM surgery and especially their quality of life (QOL) postoperatively remain undetermined.

View Article and Find Full Text PDF

Background: Trials of lumbar spondylolisthesis are difficult to compare because of the heterogeneity in the populations studied.

Objective: To define patterns of clinical presentation.

Methods: This is a study of the prospective Quality Outcomes Database spondylolisthesis registry, including patients who underwent single-segment surgery for grade 1 degenerative lumbar spondylolisthesis.

View Article and Find Full Text PDF

Objective: Reduction of Meyerding grade is often performed during fusion for spondylolisthesis. Although radiographic appearance may improve, correlation with patient-reported outcomes (PROs) is rarely reported. In this study, the authors' aim was to assess the impact of spondylolisthesis reduction on 24-month PRO measures after decompression and fusion surgery for Meyerding grade I degenerative lumbar spondylolisthesis.

View Article and Find Full Text PDF

Objective: Optimizing patient discharge after surgery has been shown to impact patient recovery and hospital/physician workflow and to reduce healthcare costs. In the current study, the authors sought to identify risk factors for nonroutine discharge after surgery for cervical myelopathy by using a national spine registry.

Methods: The Quality Outcomes Database cervical module was queried for patients who had undergone surgery for cervical myelopathy between 2016 and 2018.

View Article and Find Full Text PDF

Objective: The ideal surgical management of grade I lumbar spondylolisthesis has not been determined despite extensive prior investigations. In this cohort study, the authors used data from the large, multicenter, prospectively collected Quality Outcomes Database to bridge the gap between the findings in previous randomized trials and those in a more heterogeneous population treated in a typical practice. The objective was to assess the difference in patient-reported outcomes among patients undergoing decompression alone or decompression plus fusion.

View Article and Find Full Text PDF