Publications by authors named "Jonathan R Katz"
Article Synopsis
- The assembly of small molecules into larger structures relies on noncovalent interactions and has various practical applications, including fluorescence assays and gas storage.
- Researchers used nuclear magnetic resonance spectroscopy to study how a small-molecule probe (fluorophenol) interacts with sunset yellow across different concentrations.
- The findings revealed that adding fluorophenol does not significantly change the aggregation behavior of sunset yellow.
The interaction of small molecules with non-covalent assemblies is of wide interest. The use of a magnetically active reporter nucleus allows information to be obtained in the presence of spectral overlap or in cases of high dynamic range. In this paper, we explore the interaction of a larger probe molecule, 6-fluoro-2-naphthoic acid with assemblies of sunset yellow using (19)F chemical shifts and diffusion NMR methods.
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- The study explores how small molecules interact with larger noncovalent assemblies, specifically examining the interaction of fluorophenol isomers with sunset yellow, which forms noncovalent aggregates.
- Researchers used two NMR spectroscopic methods to analyze these interactions, leveraging the fluorine-19 nucleus as a means to track changes in chemical shifts and diffusion coefficients.
- Results suggest that at low concentrations, fluorophenol binds to sunset yellow aggregates in an end-on fashion, while at higher concentrations, it tends to insert into the stacks of the aggregates.