Publications by authors named "Jonathan Piard"

Article Synopsis
  • - The study investigates the role of TCTP (translationally controlled tumor protein) in regulating oncogenic intercellular signaling through extracellular vesicles (EVs), particularly in response to genotoxic stress.
  • - Researchers used a Tctp-inducible knockout mouse model and found that TCTP is crucial for triggering apoptosis signaling and promoting malignant growth via small EVs (sEVs).
  • - The findings suggest that TCTP enhances tumor development by binding to DDX3 and recruiting RNAs, including miRNAs, to sEVs, and inhibiting TCTP can improve survival rates in tumor-prone mice.
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New fluorescent molecular liquids with a tetrazine core have been prepared. These compounds remain liquid at least down to -60 °C and display very low viscosities (28 mPa.s for liquid 1, 58 mPa.

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A convenient protocol has been developed to fabricate well-defined nanorods of a photochromic molecule N-(3,5-di-tert-butylsalicylidene)-4-aminopyridine (DBSAP) by a laser ablation method. Reversible and fatigue-resistant optical switching and SHG activity were demonstrated. Interestingly, it was observed that DBSAP nanorods exhibit intermediate photochromic properties compared to solution and solid.

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Quantification of the relative composition of the isomers in a photochromic system at any irradiation time interval is a critical issue in determining absolute quantum yields. For this purpose, we have developed a simple and convenient protocol involving combination of UV-visible and infra-red absorption spectroscopy. Photochromic cyclization reaction of cis-l,2-dicyano-l,2-bis(2,4,5-trimethyl-3-thieny1)ethene (CMTE) is analyzed to demonstrate the efficiency of the proposed methodology.

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