Prospective, population-based study of occupational movements and postures of the neck as risk factors for cervical disc herniation.

Objective: We studied the associations between objectively measured occupational neck exposures in a job exposure matrix (JEM) and cervical disc herniation (CDH).

Design: A cohort study of Danish workers who ever held at least one of 29 jobs (eg, dentists, hairdressers, childcare, carpenters) from 1981 to 2016 was formed. Representative whole work-day inclinometric measurements from previous studies using triaxial accelerometers measuring neck angular velocity and posture of the neck were used as exposure in a JEM.

Reliability and validity of expert assessments of hand-wrist physical exposures.

Background: General population job-exposure matrices (JEMs) based on expert assessments of physical exposures may be valuable tools for studying occupation-related musculoskeletal disorders. Wrist-hand JEMs are few and the reliability and validity of expert assessments of wrist-hand exposures is uncertain.

Methods: We examined intra- and inter-rater reliability of ratings of five experts of hand-wrist repetition, deviation, force, vibration, and computer work in 33 jobs selected to represent a large exposure variation.

Early Occupational Intervention for People with Low Back Pain in Physically Demanding Jobs: 1-year Follow-up Results of the Randomized Controlled GOBACK Trial.

Study Design: Randomized controlled trial with 1-year follow up.

Objective: The aim of this study was to assess whether people with low back pain (LBP) and self-reported physically demanding jobs, benefit from an occupational medicine intervention, in addition to a single hospital consultation and a magnetic resonance imaging, at 1 year of follow-up. Secondly, to examine whether the positive health effects, found in both groups at 6 months, persist at 1-year follow-up.

Physical demand at work and sick leave due to low back pain: a cross-sectional study.

Objectives: To investigate if self-reported high physical demand at work, objective physical workload using a job exposure matrix (JEM) and fear-avoidance beliefs are associated with reported sick leave in the previous year in persons with low back pain (LBP). Second, to investigate if the effects of fear-avoidance and self-reported high physical demand at work on sick leave are modified by the objective physical workloads.

Settings: Participants were recruited from general practice and by advertisement in a local newspaper.

[Indications for orogastric emptying in poisonings are rarely present].

Orogastric aspiration (OA) without orogastric lavage has been the traditional gastric emptying method of choice in Denmark; this being based on national historic studies on poisoned patients. The treatment is still observed to be initiated prior to consultations with the Danish poisons information centre. In this review, we present relevant knowledge in the field of OA.

A detailed family history of myocardial infarction and risk of myocardial infarction--a nationwide cohort study.

Background: Family history of myocardial infarction (MI) is an independent risk factor for MI. Several genetic variants are associated with increased risk of MI and family history of MI in a first-degree relative doubles MI risk. However, although family history of MI is not a simple dichotomous risk factor, the impact of specific, detailed family histories has not received much attention, despite its high clinical relevance.

[Non-occupational pleural mesothelioma].

Asbestos fibres is the only known cause of malignant mesothelioma (MM). The risk of MM is increased also by low and brief exposure. MM has a latency of 20-50 years.

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number.

Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of scalable and practical technologies for digital PCR implementation has hampered the widespread adoption of this inherently powerful technique. Here we describe a high-throughput droplet digital PCR (ddPCR) system that enables processing of ~2 million PCR reactions using conventional TaqMan assays with a 96-well plate workflow.