Publications by authors named "Jonathan Ogle"

Article Synopsis
  • - Sarcopenia, a condition involving muscle loss, is common in men with liver cirrhosis and has negative effects on health, including increasing the risk of hepatic encephalopathy (HE); androgen receptor agonists (ARAs) like LPCN 1148 show potential to address these issues but their effectiveness and safety in this demographic were previously unclear.
  • - In a phase 2 trial, men with cirrhosis and sarcopenia were given either LPCN 1148 or placebo for 24 weeks, with results indicating that those taking LPCN 1148 had a significant increase in muscle mass (measured by CT scans) and experienced fewer episodes of serious HE compared to the placebo group.
View Article and Find Full Text PDF

Self-doping is a particular doping method that has been applied to a wide range of organic semiconductors. However, there is a lack of understanding regarding the relationship between dopant structure and function. A structurally diverse series of self-n-doped perylene diimides (PDIs) is investigated to study the impact of steric encumbrance, counterion selection, and dopant/PDI tether distance on functional parameters such as doping, stability, morphology, and charge-carrier mobility.

View Article and Find Full Text PDF

Methylammonium lead halide perovskite-based solar cells have demonstrated efficiencies as high as 24.2 %, highlighting their potential as inexpensive and solution-processable alternatives to silicon solar cell technologies. Poor stability towards moisture, ultraviolet irradiation, heat, and a bias voltage of the perovskite layer and its various device interfaces limits the commercial feasibility of this material for outdoor applications.

View Article and Find Full Text PDF