Ability of Nicotinamide Riboside to Prevent Muscle Fatigue of Barrows Subjected to a Performance Test.

The objective of this study was to determine the daily dietary nicotinamide riboside (NR) dose required to maximize the delay of subjective muscle fatigue onset. Barrows ( = 100) were assigned to one of five treatments: a conventional swine finishing diet containing 0 (CON), 15 (15NR), 30 (30NR), 45 (45NR) mg·kg body weight·d NR, or CON supplemented with 45 mg·kg body weight·d NR by drench or cookie dough (DRE). All treatments were administered for the final 11 days of feeding.

A novel class of gas separation membrane based on organic ionic plastic crystals.

The first use of organic ionic plastic crystals (OIPCs) as CO separation membranes is reported. The novel OIPC/PVDF nanofiber composites show CO/N ideal selectivities of 30 at 35 °C. The dependence of gas permeability on the thermal phase of the plastic crystals is discussed.

A novel osteotropic biomaterial OG-PLG: Synthesis and in vitro release.

Statins (e.g., simvastatin) have shown to induce expression of the bone morphogenic protein-2 gene in bone cells, but they are not used clinically because of a lack of a suitable delivery device.

A novel osteotropic biomaterial OG-PLG: in vitro efficacy.

Previously, a novel osteotropic biomaterial, OG-PLG [simvastatin grafted to poly(lactide-co-glycolide), PLG], was synthesized and shown to have degradation-controlled release kinetics. The objective here was to determine the effect of grafting statins to PLG on bone regeneration in vitro. Rat bone marrow cells were stimulated in vitro with simvastatin dissolved in media, saponified simvastatin dissolved in media, simvastatin released through diffusion from emulsion freeze-dried scaffolds, and OG-PLG.