Publications by authors named "Jonathan Marey"
Article Synopsis
- COVID-19 infections can lead to serious inflammation and potential cardiac injury, with factors like biological sex possibly influencing outcomes for patients in the ICU.
- A study of 198 ICU patients revealed that 60% experienced cardiac injury, showing no significant differences between men and women in this regard.
- Patients with cardiac injury had more cardiovascular risk factors and higher mortality rates, along with notable differences in inflammation and lymphocyte levels upon admission.
Pulmonary sequelae as assessed by pulmonary function tests (PFTs) are often reported in patients infected by SARS-CoV-2 during the post-COVID-19 period. Little is known, however, about the status of pulmonary inflammation during clinical recovery after patients' discharge from the hospitals. We prospectively measured PFTs coupled with the exhaled nitric oxide (NO) stemming from the proximal airways (FeNO) and the distal lung (CaNO) in 169 consecutive patients with varying degrees of the severity of COVID-19 six weeks to one year after acute infection by SARS-CoV-2.
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- The flu surveillance system in France is inconsistent across regions, highlighting the need for better data tracking during flu seasons.
- An exploratory study analyzed the impact of influenza on adult critical care patients at AP-HP during the 2017-2018 season, with findings showing low vaccination rates and high mortality among ICU patients.
- By using clinical data from electronic medical records, hospitals could improve patient management and enhance capacity for treating severe respiratory diseases, emphasizing the importance of real-time data in critical care settings.
Introduction: Covid-19 pneumonia CT extent correlates well with outcome including mortality. However, CT is not widely available in many countries. This study aimed to explore the relationship between Covid-19 pneumonia CT extent and blood tests variations.
View Article and Find Full Text PDFHeterozygous missense mutations in coatomer protein subunit α, COPA, cause a syndrome overlapping clinically with type I IFN-mediated disease due to gain-of-function in STING, a key adaptor of IFN signaling. Recently, increased levels of IFN-stimulated genes (ISGs) were described in COPA syndrome. However, the link between COPA mutations and IFN signaling is unknown.
View Article and Find Full Text PDFSigns and symptoms of pulmonary embolism (PE) are not specific and this can lead to a diagnostic delay. Little is known about the determinants of this delay and its prognostic implication. We conducted a retrospective analysis of a prospective cohort involving 514 patients with a first episode of PE.
View Article and Find Full Text PDFThe prognosis of multidetector computed tomography (MDCT) assessed right ventricular dilatation (RVD) is unclear in patients with pulmonary embolism (PE) and a simplified Pulmonary Embolism Severity Index (sPESI) of 0. We investigated in these patients whether MDCT-assessed RVD, defined by a right to left ventricular ratio (RV/LV) ≥0.9 or ≥1.
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