Publications by authors named "Jonathan M Pell"

Article Synopsis
  • Clinical decision support (CDS) alerts in electronic health records aim to reduce drug-induced long QT syndrome (diLQTS) risk by notifying providers when high-risk medications are prescribed.
  • During a study period, these alerts were triggered 15,002 times; however, over half of the providers (51%) chose to override the alerts and prescribe the medications anyway.
  • Factors like patient age and the availability of alternative medications influenced provider responses to the alerts, highlighting the need to balance adherence to CDS alerts with real patient outcomes like mortality rates.
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Problem: The morbidity and mortality (M&M) conference is a vital event that can affect medical education, quality improvement, and peer review in academic departments. Historically, M&M conferences have emphasized cases that highlight diagnostic uncertainty or complex management conundrums. In this report, the authors describe the development, pilot, and refinement of a systems-based M&M conference model that combines the educational and clinical missions of improving quality and patient safety in the University of Colorado Department of Medicine.

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Delivering useful clinical decision support to providers who are ordering high risk drugs for high risk patients is imperative for safe pharmacotherapy. This paper presents a focused electronic clinical decision support intervention designed to decrease the risk of corrected QT interval (QTc) related adverse drug events in a high risk patient population. Results showed that a customized alert can both decrease the number of alerts sent to providers while still improving the safety of prescribing practices for intravenous haloperidol.

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