Publications by authors named "Jonathan Laussen"

Background: Health-related quality of life (HRQoL) and absence of depressive symptoms are of great importance for older people, which may be achieved through lifestyle interventions, e.g., exercise and nutrition interventions.

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Background: The Lifestyle Interventions and Independence for Elders (LIFE) clinical trial demonstrated that a structured program of physical activity (PA) reduced mobility-disability in older adults by up to 28%. It remains unknown whether the benefits of LIFE PA can be translated to older adults at risk for mobility-disability in real-world community-based settings. To address this knowledge gap, we conducted the ENhancing independence using Group-based community interventions for healthy AGing in Elders (ENGAGE) pilot study and examined the safety, feasibility, and preliminary effectiveness of translating LIFE PA to a community-based senior center.

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Article Synopsis
  • The study aimed to investigate a possible link between blood group B and congenital cardiac defects in a larger group of patients, following earlier observations in a small sample of African-American children.
  • Researchers analyzed data from 1,985 patients undergoing cardiac surgery, categorizing them into six diagnostic subgroups, and compared their ABO blood group distributions to those found in the general U.S. population.
  • The findings revealed no significant relationship between ABO blood phenotypes and congenital cardiac defects, suggesting that the earlier reported association may not hold true in a larger, more diverse population.
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