Real-world data of a digitally enabled, time-restricted eating weight management program in public sector workers living with overweight and obesity in the United Kingdom: A service evaluation of the Roczen program.

Introduction: The health of the United Kingdom workforce is key; approximately 186 million days are lost to sickness each year. Obesity and type 2 diabetes (T2D) remain major global health challenges. The aim of this retrospective service evaluation was to assess the impact of a digitally enabled, time-restricted eating (TRE) intervention (Roczen Program, Reset Health Ltd) on weight and other health-related outcomes.

Endobronchial indocyanine green instillation to identify the intersegmental plane for successful segmentectomy.

The traditional indications for lobectomy for resectable Non-small Cell Lung Cancer (NSCLC) may be set to change. Recently, anatomical segmentectomy (AS) versus lobectomy as an approach for early-stage NSCLC has been described in phase 3 randomised controlled trials. The demand for methods to facilitate AS may increase as a consequence.

Update to the design and methods of the PATH Study, Wave 4 (2016-2017).

The Population Assessment of Tobacco and Health (PATH) Study is a nationally representative study of the US population on tobacco use and its effects on health, with four waves of data collection between 2013 and 2017. Prior work described the methods of the first three waves. In this paper, we describe the methods of Wave 4, during which a replenishment sample was added to the ongoing cohort.

Adult perceptions of the relative harm of tobacco products and subsequent tobacco product use: Longitudinal findings from waves 1 and 2 of the population assessment of tobacco and health (PATH) study.

Objectives: To examine: (1) How perceptions of harm for seven non-cigarette tobacco products predict subsequent use; (2) How change in use is associated with changes in perceptions of product harm; (3) Whether sociodemographic variables moderate the association between perceptions and use.

Methods: Data are from the adult sample (18+) of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative longitudinal cohort survey conducted September 2013-December 2014 (Wave 1 (W1) n = 32,320) and October 2014-October 2015 (Wave 2 (W2) n = 28,362).

Results: Wave 1 users and non-users of e-cigarettes, filtered cigars, cigarillos, and pipes, who perceived these products as less harmful had greater odds of using the product at W2.

U.S. adult perceptions of the harmfulness of tobacco products: descriptive findings from the 2013-14 baseline wave 1 of the path study.

Introduction: This study is the first nationally representative survey of U.S. adults (18+) to examine perceptions of the relative harms of eight non-cigarette tobacco products.

Tobacco-Product Use by Adults and Youths in the United States in 2013 and 2014.

Background: Noncigarette tobacco products are evolving rapidly, with increasing popularity in the United States.

Methods: We present prevalence estimates for 12 types of tobacco products, using data from 45,971 adult and youth participants (≥12 years of age) from Wave 1 (September 2013 through December 2014) of the Population Assessment of Tobacco and Health (PATH) Study, a large, nationally representative, longitudinal study of tobacco use and health in the United States. Participants were asked about their use of cigarettes, e-cigarettes, traditional cigars, cigarillos, filtered cigars, pipe tobacco, hookah, snus pouches, other smokeless tobacco, dissolvable tobacco, bidis, and kreteks.

Design and methods of the Population Assessment of Tobacco and Health (PATH) Study.

Background: This paper describes the methods and conceptual framework for Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study data collection. The National Institutes of Health, through the National Institute on Drug Abuse, is partnering with the Food and Drug Administration's (FDA) Center for Tobacco Products to conduct the PATH Study under a contract with Westat.

Methods: The PATH Study is a nationally representative, longitudinal cohort study of 45 971 adults and youth in the USA, aged 12 years and older.

Ethnic and gender differences in farm tasks and safety practices among rural California farm youth.

Agricultural work is hazardous and is common among rural youth, especially those living on farms or ranches. Previous work has shown differences in farm work and injury patterns between boys and girls, but little data exist addressing ethnic differences. This study examined ethnic and gender differences in farm tasks, safety attitudes, and use of protective measures among rural California youth working on farms or ranches.

Agricultural injury risk among rural California public high school students: prospective results.

Objectives: To characterize prospective agricultural injury experience among rural California Central Valley public high school students enrolled in agricultural sciences curriculum.

Methods: The University of California, Davis Youth Agricultural Injury Study (UCD-YAIS) examined prospective farm-work injury among students from 10 California Central Valley public high schools.

Results: Of eligible subjects, 882 (62.

Agricultural injury among rural California public high school students.

Objectives: The University of California, Davis Youth Agricultural Injury Study characterized the farm work and agricultural injury experience among rural California Central Valley public high school students enrolled in an agricultural sciences curriculum.

Methods: We conducted a cross-sectional survey of agricultural injury among students from 10 California Central Valley high schools during the 2001-2005 school years.

Results: Of 1,783 subjects, 946 (53.

The use of ion-milling to control clustering of nanostructured, columnar thin films.

We present the use of ion-milling to reduce the capillary-induced clustering of vertical post nanostructures grown by glancing angle deposition. Nanostructures of several heights were grown and ion-milled for various times to investigate effects on post clustering. No clustering was observed given sufficient ion-mill exposure time, with the characteristic time being lower for shorter posts.

Mortality of nontarget arthropods from an aerial application of pyrethrins.

Mortality of nontarget organisms from an ultra-low volume (ULV) aerial application of pyrethrins (Evergreen EC 60-6) was monitored by collecting arthropods from ground tarps placed at the interface of open and canopy areas. A larger number and greater diversity of arthropods were recovered from tarps in the ULV spray area. The observed mortality was approximately 10-fold greater than in the control area.

Anaemia management with subcutaneous epoetin delta in patients with chronic kidney disease (predialysis, haemodialysis, peritoneal dialysis): results of an open-label, 1-year study.

Background: Anaemia is common in patients with chronic kidney disease (CKD) and can be managed by therapy with erythropoiesis-stimulating agents (ESAs). Epoetin delta (DYNEPO, Shire plc) is the only epoetin produced in a human cell line. The aim of this study was to demonstrate the safety and efficacy of subcutaneously administered epoetin delta for the management of anaemia in CKD patients (predialysis, peritoneal dialysis or haemodialysis)

Methods: This was a 1-year, multicentre, open-label study.

Albumin induces interleukin-6 release from primary human proximal tubule epithelial cells.

Background: Proximal tubule epithelial cells (PTECs) release proinflammatory and profibrogenic mediators when exposed to serum albumin that may contribute to progression of kidney disease. Interleukin 6 (IL-6) may influence renal fibrosis by modulating transforming growth factor beta1 (TGFbeta1) signalling. PTECs have been demonstrated to produce IL-6 in response to albumin treatment, but the mechanism has not been investigated.

Healthcare resource utilization for anemia management: current practice with erythropoiesis-stimulating agents and the impact of converting to once-monthly C.E.R.A.

Unlabelled: Background andMethods: A prospective, observational study in 12 German and UK dialysis centers which quantified personnel time for anemia treatment using erythropoiesis-stimulating agents (ESAs). Tasks directly observable were measured through the time-and-motion method; time for non-observable tasks was estimated by healthcare staff. Using activity-based costing methods, time was converted into monetary units.

Long-term efficacy and safety profile of lanthanum carbonate: results for up to 6 years of treatment.

Background/aims: Lanthanum carbonate (LC, FOSRENOL) is an effective phosphate binder for which tolerability and a safety profile have been reported in haemodialysis patients. Patients from previous studies entered a 2-year extension, enabling assessment of efficacy and safety for up to 6 years of LC monotherapy.

Methods: Patients from four previous trials entered this study.

Development time of Culex mosquitoes in stormwater management structures in California.

A widely recommended strategy to minimize mosquito production in structural stormwater Best Management Practices (BMPs) is to ensure they hold captured water for no more than 72 h. However, this standard may be overly conservative for many mosquito species found in urban environments and may impede or prevent the capacity of BMPs to fulfill more stringent water quality standards in environmentally sensitive areas. Egg-to-pupa development of Culex tarsalis, Cx.

Mosquito production in stormwater treatment devices in the Lake Tahoe Basin, California.

In response to increasing evidence of mosquito production in structural stormwater Best Management Practices (BMPs), a collaborative project was developed to document the occurrence, species composition, and seasonal abundance of mosquitoes from selected urban and highway BMPs in the Lake Tahoe Basin, California. Structural and environmental factors associated with mosquito production in highway BMPs were identified and analyzed. Ten species of mosquitoes were collected from 47 BMPs, including Culex tarsalis, Culiseta incidens, Cs.

BMP-7 and proximal tubule epithelial cells: activation of multiple signaling pathways reveals a novel anti-fibrotic mechanism.

Purpose: Bone morphogenic protein-7 (BMP-7) is a member of the transforming growth factor beta (TGFbeta) superfamily involved in organogenesis. Recent work suggests that BMP-7 can reverse the fibrotic effects of TGFbeta but the underlying mechanism is unknown. We sought to determine BMP-7 signaling and its modulation of TGFbeta induced fibrotic outcomes in adult human proximal tubule epithelial cells (PTECs).

Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients.

Objective: To demonstrate safety and efficacy of epoetin delta for the management of anaemia in predialysis patients with chronic kidney disease (CKD).

Research Design And Methods: This was a multicentre, open-label, uncontrolled study with predialysis CKD patients who had previously received subcutaneous epoetin therapy. Patients were switched to epoetin delta from their previous therapy, at an identical dose.

Is early treatment of anaemia with epoetin-alpha beneficial to pre-dialysis chronic kidney disease patients? Results of a multicentre, open-label, prospective, randomized, comparative group trial.

Background: This multicentre, open-label prospective, randomized, comparative-group study evaluated the effects of maintaining haemoglobin (Hb) in pre-dialysis chronic kidney disease (CKD) patients.

Methods: A total of 197 patients were randomized to start subcutaneous epoetin-alpha (SC-EPO; EPREX; 1000 U twice weekly) at an early stage of anaemia to maintain Hb at 11.0 +/- 1.