Publications by authors named "Jonathan G Piccirillo"
Article Synopsis
- Macrophages are crucial immune cells that help maintain tissue health, defend against pathogens, and their function can be influenced by their metabolism.
- The study uses various advanced imaging and biochemical techniques to explore how growth hormone (GH) affects the metabolism of inflamed macrophages.
- Results show that GH reprograms these inflammatory macrophages by reducing their metabolism and enhancing mitochondrial function, indicating that targeting macrophage metabolism could be a new strategy for treating inflammatory diseases.
