Publications by authors named "Jonathan De Souza"
Artificial intelligence in mammography: a systematic review of the external validation.
Rev Bras Ginecol Obstet
October 2024
Article Synopsis
- The study aimed to review how different Artificial Intelligence algorithms perform in validating mammography for breast cancer screening through a systematic analysis of existing research.
- After searching major medical databases and filtering through thousands of articles, 30 relevant studies were selected for analysis over the past decade.
- The findings indicated that AI algorithms can match radiologists in accuracy and even improve mammogram evaluations when used alongside them, aiding both experienced and less experienced medical professionals in detecting potential lesions.
Bacterial and viral infections are serious public health issue. Therefore, this study aimed to evaluate the antibacterial, antibiofilm and antiviral potential of the Brazilian Red Propolis (BRP) crude hydroalcoholic extract, fractions, and isolated compounds, as well as their in vivo toxicity. The antibacterial activity was evaluated by determining the Minimum Inhibitory Concentration and the antibiofilm activity by determining the Minimum Inhibitory Concentration of Biofilm (MICB).
View Article and Find Full Text PDFIn the present work, the synthesis, characterization, antifungal activity, molecular docking study and in silico approach of five thiosemicarbazone derivatives and their corresponding zinc(II) complexes are described. The compounds were characterized by elemental analysis, IR, UV-Vis and NMR spectroscopic measurements, molar conductivity measurements, emission spectra, high-resolution mass spectrometry and X ray study. The antifungal activity of the free ligands and synthesized compounds was preliminarily evaluated against Candida albicans (ATCC 90028), Candida tropicalis (ATCC 13803) and Candida glabrata (ATCC 2001), by the minimum inhibitory concentration (MIC) assay.
View Article and Find Full Text PDFThe genus Absidia is widely used in the biotransformation of different classes of natural products. This study evaluates the ability of the Absidia coerulea 3A9 marine derived strain isolated from the ascidian Distaplia stilyfera to perform biotransformations by conducting assays with (-)-cubebin, as substrate. The experiment was optimized using the experimental design proposed by Plackett-Burman for seven factors and eight experiments, to establish the biotransformation conditions that would allow maximum production of biotransformed dibenzylbutyrolactone (-)-hinokinin.
View Article and Find Full Text PDFBackground: Sleeve gastrectomy (SG) has been used for the surgical treatment of morbid obesity, as a first step or as a definitive treatment. The objective of this pilot study was to establish an animal model for SG in Wistar rats.
Methods: 12 male Wistar rats were operated on.