Publications by authors named "Jonathan D Merran"
Article Synopsis
- The study investigates RNA splicing fidelity and highlights the role of various proteins, including TDP-43, PTBP1, and PTBP2, in repressing nonconserved cryptic exons.
- While TDP-43 uses UG microsatellites for repression, PTBP1 and PTBP2 use CU microsatellites to target both conserved tissue-specific and nonconserved cryptic exons.
- The findings suggest that PTBP1 and PTBP2 are part of a larger family of splicing factors that help regulate transcript diversity necessary for neuronal differentiation.
