Publications by authors named "Jonathan C Collard de Beaufort"

Article Synopsis
  • Osteogenesis imperfecta (OI) is a genetic disorder that makes bones fragile and can lead to easy fractures, alongside issues with blood vessels and platelets.
  • This case highlights the first successful use of a flow diversion technique for treating brain aneurysms in a 62-year-old female patient with OI Type I, who had a long history of fractures and was being treated for transient ischemic attacks.
  • After successfully treating two aneurysms with devices, the patient showed complete obliteration of both, remained asymptomatic, and had no complications during the five years of follow-up.
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Background: The delivery of neuroendovascular devices requires a robust proximal access platform. This demand has previously been met with a 6Fr long sheath (8Fr guide) that is placed in the proximal internal carotid artery (ICA) or vertebral artery segments. We share our experience with the first 0.

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Formation of a carotid free-floating thrombus (CFFT) is a rare and life-threatening condition without an optimal management plan. A 78-year-old woman with a history of prior right internal carotid artery (ICA) mechanical thrombectomy and antiplatelet noncompliance presented with transient ischemic attacks secondary to a recurrent CFFT in the right ICA. Given her symptoms and recurrent CFFT, endovascular mechanical thrombectomy was performed.

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Background: Endovascular embolization of the middle meningeal artery (MMA) has emerged as an adjunctive and stand-alone modality for the management of chronic subdural hematomas (cSDH). We report our experience utilizing proximal MMA coil embolization to augment cSDH devascularization in MMA embolization.

Methods: MMA embolization cases with adjunctive proximal MMA coiling were retrospectively identified from a prospectively maintained IRB-approved database of the senior authors.

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Article Synopsis
  • The approach to using dual antiplatelet therapy (DAPT) during procedures for managing intracranial aneurysms has changed significantly, as new techniques have developed.
  • Traditionally, aspirin and clopidogrel were the preferred medications, but recent findings suggest that DAPT should be customized based on each patient's specific factors that affect clopidogrel metabolism, like genetic differences.
  • A review of 368 studies indicates a growing interest in alternative DAPT medications, such as ticagrelor, tirofiban, and prasugrel, which are effective and safe options that don't need enzymatic activation, though more clinical trials are needed to create strong evidence-based guidelines.
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