Distribution of and chloroquine drug resistance alleles in north-western Nigeria.

Background: In Nigeria, decline in the sensitivity of to Artemisinin Combination Therapy (ACT) has prompted the unofficial use of chloroquine (CQ) for self-medication. This study was designed to determine the prevalence and distribution of CQ resistant/susceptible alleles of CQ resistance transporter () and multidrug resistance gene 1 () in view of the possible re-introduction of CQ for malaria treatment.

Materials And Methods: Four hundred and sixty six (466) positive samples were randomly collected from five states of northwest Nigeria.