Prone cylindrical abdominoperineal resection with subsequent rectus abdominis myocutaneous flap reconstruction performed by a colorectal surgeon.

Purpose: Prone cylindrical abdominoperineal resection (APR) leads to reduced circumferential resection margin (CRM) involvement but is associated with a large perineal deficit. A rectus abdominis myocutaneous (RAM) flap can reduce the morbidity associated with the perineal wound. This is often performed in coordination with a plastic surgeon.

Gastric necrosis complicating acute gastric dilatation after Nissen fundoplication.

A woman in her 70s was referred for the management of complex intestinal fistulation, which had developed as a postoperative complication of laparoscopic Nissen fundoplication. Surgical treatment of a jejunocolocutaneous fistula and formation of a double-barrelled ileocolostomy was undertaken uneventfully. Routine postoperative nasogastric intubation was not undertaken.

An algorithm for constraint-based structural template matching: application to 3D templates with statistical analysis.

Motivation: Structural templates consisting of a few atoms in a specific geometric conformation provide a powerful tool for studying the relationship between protein structure and function. Current methods for template searching constrain template syntax and semantics by their design. Hence there is a need for a more flexible core algorithm upon which to build more sophisticated tools.

Celiac artery compression by the median arcuate ligament: a pitfall of end-expiratory MR imaging.

Purpose: To measure the prevalence and degree of celiac artery compression during breath-hold imaging at end inspiration and end expiration in patients referred to undergo magnetic resonance (MR) imaging of the abdomen for reasons unrelated to intestinal ischemia.

Materials And Methods: A series of 100 patients underwent routine MR imaging of the upper abdomen at 1.5 T; imaging included multiple dynamic contrast-enhanced fat-suppressed transverse three-dimensional spoiled gradient-echo acquisitions (3.

Using structural motif templates to identify proteins with DNA binding function.

This work describes a method for predicting DNA binding function from structure using 3-dimensional templates. Proteins that bind DNA using small contiguous helix-turn-helix (HTH) motifs comprise a significant number of all DNA-binding proteins. A structural template library of seven HTH motifs has been created from non-homologous DNA-binding proteins in the Protein Data Bank.