Regular endurance training may enhance immune responses in the respiratory tract compared to a sedentary lifestyle, especially after exposure to particulate matter (PM).
The study analyzed nasal lavage fluid and other immune markers in street runners and sedentary individuals after both acute and chronic PM exposure.
Results showed that runners had healthier immune responses, indicated by lower inflammatory markers and higher protective factors, aligning with a Th1 immune response, while sedentary individuals showed a Th2 pattern associated with increased inflammation.