Publications by authors named "Jonas Pachmann"
Article Synopsis
- A retrospective study assessed the diagnostic effectiveness of C-reactive protein (CRP) and leucocyte count in differentiating complicated (CAA) from uncomplicated acute appendicitis (UAA) based on EAES guidelines, involving 285 patients in Germany from 2019 to 2021.
- The study found that CRP levels were significantly higher in CAA patients compared to UAA patients, showing medium diagnostic value for identifying CAA and a cutoff at 44.3 mg/L, while leucocyte count had a low predictive value.
- Higher CRP levels were linked to an increased risk of postoperative complications and longer hospital stays, indicating that CRP is a useful marker for diagnosing CAA within the EA
: In patients diagnosed with uncomplicated acute appendicitis (UAA), the absence of calcified deposits or stones, called appendicoliths, often leads to consideration of non-operative treatment (NOT), despite the notable treatment failure rate associated with this approach. Previous research has indirectly estimated the prevalence of appendicoliths to range between 15% and 38% retrospectively by CT scan, intraoperative palpation, and pathology report, thereby potentially missing certain concrements. Our hypothesis proposes that this reported prevalence significantly underestimates the occurrence of appendicoliths, which could explain the high failure rate of 29% of patients with appendicitis observed with NOT.
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