Investigation of the effectiveness of prehospital amputation devices on cadavers.

Amputations take place in the operating rooms. At dangerous sites, circumstances may necessitate on-site amputation to save lives. Currently, there are no evidence-based guidelines for the execution of the amputation or the instruments to be chosen.

Resilience throughout COVID-19: Unmasking the realities of COVID-19 and vaccination facilitators, barriers, and attitudes among Black Canadians.

Black communities have suffered disproportionately higher numbers of COVID-19 cases and deaths in Canada. Recognizing the significance of supporting targeted strategies with vulnerable populations extends beyond the COVID-19 pandemic, as it addresses longstanding health disparities and promotes equitable access to healthcare. The present study investigated 1) experiences with COVID-19, 2) COVID-19's impact, and 3) factors that have influenced COVID-19 vaccine acceptance and uptake among stakeholders and partners from the Federation of Black Canadians' (FBC).

Examining the barriers, facilitators and attitudes towards COVID-19 vaccine and public health measures for black communities in Canada: a qualitative study protocol.

Introduction: Black communities claim the highest number of cases and deaths due to COVID-19 in Canada. Generating culturally/contextually appropriate public health measures and strategies for vaccine uptake in black communities within Canada can better support the disproportionate impact of this pandemic. This study explores the barriers and enablers to public health measures limited to mask-wearing, disinfection, sanitation, social distancing and handwashing, as well as the barriers and attitudes towards COVID-19 vaccines among the black community.

Augmenting the Sensing Performance of Entangled Photon Pairs through Asymmetry.

We analyze theoretically and experimentally cases of asymmetric detection, stimulation, and loss within a quantum nonlinear interferometer of entangled pairs. We show that the visibility of the SU(1,1) interference directly discerns between loss on the measured mode (signal) and the conjugated mode (idler). This asymmetry also affects the phase sensitivity of the interferometer, where coherent seeding is shown to mitigate losses that are suffered by the conjugated mode; therefore increasing the maximum threshold of loss that permits sub-shot-noise phase detection.

Long-Range Mass Transport during Structural Transitions in Metallic Glass-Forming Melts.

We investigate the structure and dynamics of the bulk metallic glass-forming alloys Zr_{41.2}Ti_{13.8}Cu_{12.

High-saturated fat-sucrose feeding affects lactation energetics in control mice and mice selectively bred for high wheel-running behavior.

Feeding a diet high in fat and sucrose (HFS) during pregnancy and lactation is known to increase susceptibility to develop metabolic derangements later in life. A trait for increased behavioral activity may oppose these effects, since this would drain energy from milk produced to be made available to the offspring. To investigate these interactions, we assessed several components of behavioral energetics during lactation in control mice (C) and in mice of two lines selectively bred for high wheel-running activity (S1, S2) subjected to a HFS diet or a low-fat (LF) diet.

Behavioral traits are affected by selective breeding for increased wheel-running behavior in mice.

Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and "information gathering" in the open-field test, either with increased upright positions or horizontal locomotion toward the middle ring.

Effects of selective breeding for increased wheel-running behavior on circadian timing of substrate oxidation and ingestive behavior.

Fluctuations in substrate preference and utilization across the circadian cycle may be influenced by the degree of physical activity and nutritional status. In the present study, we assessed these relationships in control mice and in mice from a line selectively bred for high voluntary wheel-running behavior, either when feeding a carbohydrate-rich/low-fat (LF) or a high-fat (HF) diet. Housed without wheels, selected mice, and in particular the females, exhibited higher cage activity than their non-selected controls during the dark phase and at the onset of the light phase, irrespective of diet.

Optimal placement of bipolar surface EMG electrodes in the face based on single motor unit analysis.

Locations of surface electromyography (sEMG) electrodes in the face are usually chosen on a macro-anatomical basis. In this study we describe optimal placement of bipolar electrodes based on a novel method and present results for lower facial muscles. We performed high-density sEMG recordings in 13 healthy participants.

Metabolic responses to long-term pharmacological inhibition of CB1-receptor activity in mice in relation to dietary fat composition.

Background And Objectives: The antiobesity effects of suppressed endocannabinoid signaling may rely, at least in part, on changes in lipid fluxes. As fatty acids exert specific effects depending on their level of saturation, we hypothesized that the dietary fatty acid composition would influence the outcome of treatment with a CB(1)-receptor antagonist (rimonabant).

Methods: Mice were treated with rimonabant (10 mg kg(-1) body weight per day) or vehicle while equicalorically fed either a low-fat diet (LF), a high-fat (HF) diet or an HF diet in which 10% of the saturated fatty acids (SFAs) were replaced by poly-unsaturated fatty acids (PUFA) from fish oil (FO).

A randomized prospective long-term study of two oral appliances for sleep apnoea treatment.

Various types of mandibular protrusive appliances have revealed different treatment success in mild-to-moderate obstructive sleep apnoea (OSA). The present study compared the long-term effect of two different appliances in the treatment of OSA. A total of 103 patients with OSA were randomized and treated with an IST((R)) or Thornton Anterior Positioner (TAP()) appliance.

Dental side effects of mandibular advancement appliances - a 2-year follow-up.

Background And Objectives: Mandibular advancement appliances are employed in treating snoring and various forms of obstructive sleep apnea syndrome (OSAS). The splints facilitate the displacement of the mandible anteriorly and widens the pharyngeal lumen during sleep. Two-splint systems are anchored on the dental arches in the maxilla and mandible.

Metabolic and behavioral responses to high-fat feeding in mice selectively bred for high wheel-running activity.

Objective: Increased dietary fat intake is a precipitating factor for the development of obesity and associated metabolic disturbances. Physically active individuals generally have a reduced risk of developing these unhealthy states, but the underlying mechanisms are poorly understood. In the present study, we investigated the effects of feeding a high-fat diet (HFD) on obesity development and fuel homeostasis in male and female mice with a trait for increased physical activity and in their controls.

Potential of information technology in dental education.

The use of information technology (IT) in dentistry is far ranging. In order to produce a working document for the dental educator, this paper focuses on those methods where IT can assist in the education and competence development of dental students and dentists (e.g.

Dentofacial parameters explaining variability in retroclination of the maxillary central incisors.

Background And Aim: The interrelation between retroclination of the maxillary central incisors and dentofacial parameters is a controversial subject in the literature. In contrast to comparisons between malocclusion and control groups, the objective of the present study was to identify skeletal, dentoalveolar or perioral (soft-tissue) factors which primarily determine how severely retroclination is individually manifested.

Materials And Methods: For this purpose we evaluated the pretherapeutic lateral cephalograms of 83 patients with an inclination of the maxillary central incisors ranging from physiological values to very severe retroclination (inclination to anterior cranial base between 104 degrees and 64 degrees ).

Long-term stability of unilateral posterior crossbite correction.

Objective: To evaluate the stability of orthodontically corrected unilateral posterior crossbite in patients treated either by rapid maxillary expansion or with slow expansion devices in the early (mean age 7.2 years, n = 50) or late mixed dentition (mean age 9.9 years, n = 50).

One- or two-stage palate closure in patients with unilateral cleft lip and palate: comparing cephalometric and occlusal outcomes.

Objective: To assess facial growth and dentoalveolar development in two groups of patients with complete unilateral cleft lip and palate. Primary surgical treatment differed in the timing of hard palate closure.

Design: Forty-three patients with unilateral cleft lip and palate were examined.

Smart bracket for multi-dimensional force and moment measurement.

Atraumatic, well-directed, and efficient tooth movement is interrelated with the therapeutic application of adequately dimensioned forces and moments in all three dimensions. The lack of appropriate monitoring tools inspired the development of an orthodontic bracket with an integrated microelectronic chip equipped with multiple piezoresistive stress sensors. Such a 'smart bracket' was constructed (scale of 2.

Lip-to-incisor relationship and postorthodontic long-term stability of cover-bite treatment.

Objective: To investigate the impact of a persisting high lip line and other potential relapse-inducing factors on long-term stability of orthodontic correction of retroinclined maxillary central incisors.

Materials And Methods: Thirty-one cover-bite ("Deckbiss") patients with retroinclined maxillary central incisors and a deep frontal overbite were evaluated. The maxillary central incisor inclination was determined odontometrically with study models made pretreatment, posttreatment, and at a follow-up examination (mean posttherapeutic interval: 9.

Topographical characteristics of motor units of the lower facial musculature revealed by means of high-density surface EMG.

The objective of this study was to systematically characterize motor units (MUs) of the musculature of the lower face. MU endplate positions and principal muscle fiber orientations relative to facial landmarks were identified. This was done by the analysis of motor unit action potentials (MUAPs) in the surface electromyogram.

Validation of speed of sound for the assessment of cortical bone maturity.

Bone changes its structural and physical properties during maturation. In order to validate ultrasound measurements with regard to their usefulness in assessing cortical bone maturation, speed of sound (SOS) data were compared with mechanical properties (elastic modulus, bending strength, and cortical surface hardness), density and water content. Thirty pig mandibles were selected from three different age groups.

Stress, burnout and health in the clinical period of dental education.

The study examined the extent of stress, burnout and health problems experienced by fourth and fifth year dental students from the three universities of Dresden, Freiburg and Bern. The objectives of the study were to: (i) identify frequent sources of stress and to report the prevalence rates of burnout and health problems in dental students, (ii) determine the rate of students suffering from severe burnout symptoms and (iii) identify stress factors related to the burnout symptoms of emotional exhaustion and depersonalization. A total of 161 dental students from Dresden, Freiburg and Bern participated in the study.

Case control study in the treatment of obstructive sleep-disordered breathing with an intraoral protrusive appliance.

Background: Mandibular protrusive appliances have long been used to treat obstructive sleep apnea/hypopnea syndrome (OSAHS). Their efficacy regarding respiration during sleep varies greatly and remains difficult to predict. In this study the efficacy of a two-splint appliance on nocturnal breathing disorders, sleep profile, and daytime sleepiness were evaluated according to a specially-designed treatment process.

A retrospective cephalometric study for the quantitative assessment of relapse factors in cover-bite treatment.

Background And Aim: Cover-bite ("Deckbiss") is regarded as a highly relapse-prone malocclusion. In this context the great significance of a high lip line (LipL) as an etiologic factor for the retroclination of the upper central incisors was recently proven within the framework of lip pressure measurements. It therefore seemed likely that a persisting high LipL after correction of cover-bite might have an equally negative impact on the stability of the treatment outcome.

A thin, flexible multielectrode grid for high-density surface EMG.

Although the value of high-density surface electromyography (sEMG) has already been proven in fundamental research and for specific diagnostic questions, there is as yet no broad clinical application. This is partly due to limitations of construction principles and application techniques of conventional electrode array systems. We developed a thin, highly flexible, two-dimensional multielectrode sEMG grid, which is manufactured by using flexprint techniques.