Objectives: The aim of this study was to investigate the influence of xenon-based anesthesia on somatosensory-evoked potentials.
Design: Observational cohort study.
Setting: University hospital.
Background: Topical drug application is used to avoid systemic side effects. The aim of this study was to analyze whether locally applied iloprost or nitroglycerin influence gastric mucosal perfusion, oxygenation, and barrier function during physiological and hemorrhagic conditions.
Methods: In repeated experiments, 5 anesthetized dogs received iloprost, nitroglycerin, or normal saline during physiological and hemorrhagic (-20% blood volume) conditions.