Publications by authors named "Jonas Apitzsch"

Pneumothorax is one of the most frequent complications of computed tomography (CT)-guided lung biopsies. We aim to identify the safe zone of the needle-pleura angle during a CT-guided lung biopsy. Fifty-two patients underwent CT-guided lung biopsies between January 2020 and September 2022 (27 males, 25 females, median age 70 years).

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Objectives: Multiple studies show orthopedic health problems for medical staff due to wearing radiation protection aprons. The aim of this study was to evaluate the weight pressure on the shoulder as a marker of physical strain caused by different radiation-protection devices.

Methods: For the weight pressure measurement, a pressure sensor (OMD-30-SE-100N, OptoForce, Budapest, Hungary) placed on the left and right shoulder was used.

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Article Synopsis
  • The study evaluated nine factors (covariates) impacting the occurrence of stable or symptomatic pneumothorax in patients undergoing CT-guided lung biopsies.
  • A total of 43 patients participated, with an emphasis on variables such as lesion size, angle of the needle in relation to the pleura, and patient demographics.
  • Findings indicated that a smaller needle-pleura angle significantly increased the risk of pneumothorax, suggesting that optimizing this angle during procedures could reduce potential complications.
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Impalement injuries are infrequent yet tend to be life-threatening. Transorbital penetration by foreign bodies represents a peculiar form of traumatic brain injury. However, much is at stake with the high risk of neurological and ophthalmic impairment.

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Purpose: Studies have demonstrated that positron emission tomography/computed tomography (PET/CT) with Gallium-68 (68Ga)-labeled somatostatin analogues are effective at detecting metastatic disease in neuroendocrine tumors (NET), especially extrahepatic metastases. However, PET in combination with full-dose contrast-enhanced CT (ceCT) exposes patients to higher radiation (~25 mSv). The use of non-contrast-enhanced low-dose CT (ldCT) can reduce radiation to about 10 mSv and may avoid contrast-induced side effects.

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Purpose: Condylar head fractures (CHFs) are increasingly treated by open reduction and internal fixation (ORIF). However, there are no reports on the three-dimensional postoperative volumetric transformation of the condyle, especially with regard to fragmented cases. Protruding hardware can lead to severe complications, so the goal of this study was to examine the amount of condylar bony resorption occurring after ORIF.

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Background: Routine screening is recommended for patients with multiple endocrine neoplasia type 1 (MEN1) to enable early detection and treatment of associated neuroendocrine neoplasms (NEN). Gallium-DOTATOC-Positron emission tomography combined with computed tomography (Ga-68-DOTATOC-PET-CT) is a very sensitive and specific imaging technique for the detection of sporadic neuroendocrine tumors. The present study evaluated the value of Ga-68-DOTATOC-PET-CT in routine screening of patients with MEN1.

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Renal microvascular rarefaction characterizes chronic kidney disease (CKD). In murine models of CKD, micro-CT imaging reflected capillary rarefaction using quantification of renal relative blood volume (rBV). In addition, micro-CT imaging revealed morphological alterations of the intrarenal vasculature including reduced vascular branching and lumen diameter.

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Background: Biphasic injection protocols are frequently used because they yield homogenous contrast enhancement. We hypothesize that with faster scanners and shorter scan times, biphasic injection protocols are no longer necessary.

Purpose: To evaluate whether a monophasic injection protocol is equivalent to a biphasic protocol in terms of contrast enhancement and homogeneity.

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Article Synopsis
  • This study focused on bronchopulmonary neuroendocrine tumors (bNET) in patients with multiple endocrine neoplasia type 1 (MEN1) to understand their prevalence, precursor lesions, and prognosis.
  • Five out of 75 MEN1 patients (6.6%) were found to have bNET after a median follow-up of 134 months, with all cases being asymptomatic and predominantly well differentiated.
  • The findings suggest that bNET in MEN1 are more common than thought, often have a benign course, and may be preceded by multifocal neuroendocrine changes and tumorlets.
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Postmortem computed tomography (PMCT) is a modern tool that complements autopsy diagnostics. In clinical autopsies, a major cause of death is cardiovascular disease. To improve the performance of PMCT in cardiovascular disease, full body angiography was developed (PMCT angiography [PMCTA]).

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Objectives: To evaluate the diagnostic value of contrast enhanced post mortem computed tomography (PMCT) in comparison to non-enhanced post mortem CT in the detection of cardiovascular causes of death (COD).

Background: As autopsy rates decline, new methods to determine CODs are necessary. So contrast enhanced PMCT shall be evaluated in comparison to established non-enhanced PMCT in order to further improve the method.

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Objective: This study was carried out to identify groups of patients who would benefit from this angiography. The angiographic images of a random group of patients were studied; the correlations between the vascular state of the lower extremities and vessel pathology were investigated; and the possible links of these findings with certain medical conditions were explored.

Study Design: Three experienced observers independently evaluated the angiograms of 185 patients.

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Purpose: To investigate the quantitative and qualitative differences between combined positron emission tomography and computed X-ray tomography (PET/CT) enhanced with contrast medium with either an iodine concentration 300 mg/ml or 370 mg/ml.

Materials And Methods: 120 consecutive patients scheduled for F-18-Fluorodeoxyglucose (FDG) PET/CT were included. The first (second) 60 patients received contrast medium with 300 (370) mg iodine/ml.

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For the past century, autopsy techniques in clinical pathology have not changed significantly, while autopsy rates are declining. Modern imaging techniques offer interesting prospects of supportive post-mortem diagnostic investigation. In a prospective study of 29 autopsy cases, complimentary virtual autopsy using unenhanced post-mortem computed tomography (pmCT) was performed.

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We report the case of a man with an uncommon anomaly of the origin and course of the left coronary artery. Clinical, coronary angiography, magnetic resonance imaging, and multislice computed tomography findings of this intermittently symptomatic 49 year-old patient with the rare anomaly of his left coronary artery stemming from the right sinus of Valsalva and taking an interarterial and intraseptal course are presented. The diagnostic value of the different imaging modalities is discussed.

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Objective: The term "informed consent" explains the process by which a patient, before treatment, is provided comprehensive and impartial information regarding a planned operative procedure so that he/she understands the implications of the procedure before consenting. The goal of the current study was to investigate whether standard methods of consenting can be improved using a multimedia-based information program (MM-IP).

Patients And Methods: In a prospective multicenter study, 80 patients undergoing laparoscopic cholecystectomy went through the standard informed consent process.

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