Publications by authors named "Jonas A Bojsen"

Purpose: To estimate the strength of association between use of antithrombotics (AT) drugs with survival after spontaneous intracerebral hemorrhage (s-ICH) comparing oral anticoagulant (OAC) or platelet antiaggregants (PA) with no AT use and in active comparator analyses OAC vs PA, direct oral anticoagulant (DOAC) vs vitamin K antagonist (VKA), and clopidogrel vs aspirin.

Patients And Methods: We identified patients ≥55 years with a first-ever s-ICH between 2015 and 2018 in Southern Denmark (population 1.2 million).

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Objectives: This systematic review and meta-analysis aimed to assess the stroke detection performance of artificial intelligence (AI) in magnetic resonance imaging (MRI), and additionally to identify reporting insufficiencies.

Methods: PRISMA guidelines were followed. MEDLINE, Embase, Cochrane Central, and IEEE Xplore were searched for studies utilising MRI and AI for stroke detection.

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Background And Objectives: Few population-based studies have assessed associations between the use of antithrombotic (platelet antiaggregant or anticoagulant) drugs and location-specific risks of spontaneous intracerebral hemorrhage (s-ICH). In this study, we estimated associations between antithrombotic drug use and the risk of lobar vs nonlobar incident s-ICH.

Methods: Using Danish nationwide registries, we identified cases in the Southern Denmark Region of first-ever s-ICH in patients aged 50 years or older between 2009 and 2018.

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Article Synopsis
  • This study aimed to evaluate the performance of a commercial AI tool in detecting acute brain ischemia on MRI compared to a seasoned neuroradiologist.
  • Researchers analyzed MRIs from 1030 patients suspected of a stroke, ultimately focusing on 995 for their assessment.
  • Results showed the AI tool had high sensitivity (89%) and specificity (90%) for detecting ischemic lesions, although performance varied with lesion size and image quality.
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Importance: Survivors of spontaneous (ie, nontraumatic and with no known structural cause) intracerebral hemorrhage (ICH) have an increased risk of major cardiovascular events (MACEs), including recurrent ICH, ischemic stroke (IS), and myocardial infarction (MI). Only limited data are available from large, unselected population studies assessing the risk of MACEs according to index hematoma location.

Objective: To examine the risk of MACEs (ie, the composite of ICH, IS, spontaneous intracranial extra-axial hemorrhage, MI, systemic embolism, or vascular death) after ICH based on ICH location (lobar vs nonlobar).

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Background And Objectives: A causal relationship between statin use and intracerebral hemorrhage (ICH) is uncertain. We hypothesized that an association between long-term statin exposure and ICH risk might vary for different ICH locations.

Methods: We conducted this analysis using linked Danish nationwide registries.

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Article Synopsis
  • - This study compared traditional instructor-led lessons and immersive virtual reality (IVR) lessons to teach basic point-of-care ultrasound (PoCUS) skills to final-year medical students through a randomized controlled trial.
  • - Learning efficacy was measured using the Objective Structured Assessment of Ultrasound Skills (OSAUS), and results showed no significant differences in performance scores between the two teaching methods.
  • - While both courses had similar maintenance costs, the instructor-led course had much higher startup costs; the findings indicate that IVR could be a viable alternative to traditional instruction, though further research is needed.
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In this case report, a 40-year-old woman presented with altered mentation, central facial palsy and hemiparesis. Acute CT scan showed several hypodense, rounded areas in both hemispheres. Urine toxicology tested positive for amphetamine.

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Background: Cryoablation is a promising minimally invasive, nephron-sparing treatment of small renal carcinoma (RCC) in co-morbid patients.

Purpose: To assess the safety, efficacy, and cancer-specific outcomes of computed tomography (CT)-guided cryoablation of stage T1 (RCC).

Material And Methods: A retrospective evaluation of 122 consecutive patients with 128 tumors treated with cryoablation during 2016-2017.

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Brown tumors (BTs) are manifestations of osteitis fibrosa cystica that develops due to increased osteoclast activity secondary to hyperparathyroidism (HPTH). The name comes from its characteristic brown color due to high hemosiderin level and hemorrhage surrounded by osteoclastic giant cells, fibrous tissue, and bone fragments. Presentation can be either unifocal or rarely multifocal.

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