Regularized origin ensemble with a beam prior for range verification in particle therapy with Compton-camera data.

In particle therapy (PT), several methods are being investigated to help reduce range margins and identify deviations from the original treatment plan, such as prompt-gamma (PG) imaging with Compton cameras (CC). To reconstruct the images, the Origin Ensemble (OE) algorithm is commonly used. In the context of PT, artifacts and strong noise often affect CC images.

Stopping power and range estimations in proton therapy based on prompt gamma timing: motion models and automated parameter optimization.

Particle therapy treatments are currently limited by uncertainties of the delivered dose. Verification techniques like Prompt-Gamma-Timing-based Stopping Power Estimation (PGT-SPE) may allow for reduction of safety margins in treatment planning.From Prompt-Gamma-Timing measurements, we reconstruct the spatiotemporal distribution of prompt gamma emissions, which is linked to the average motion of the primary particles.