Publications by authors named "Jon M Greif"
Background: Single-dose intraoperative radiotherapy (IORT) is an emerging treatment for women with early stage breast cancer. The objective of this study was to define the frequency of IORT use, patient selection, and outcomes of patients treated in North America.
Methods: A multi-institutional retrospective registry was created, and 19 institutions using low-kilovoltage IORT for the treatment of breast cancer entered data on patients treated at their institution before July 31, 2013.
Background: Adenoid cystic carcinoma (ACC) is a rare subtype of breast malignancy.
Methods: Patients with ACC and infiltrating ductal carcinoma (IDC) reported to the National Cancer Data Base from 1998 to 2008 were reviewed for patient age, ethnicity, tumor size, nodal status, American Joint Committee on Cancer TNM Stage, tumor grade, initial treatment, hormone receptor status (for patients from 2004 to 2008), and survival (for patients from 1998 to 2003).
Results: A total of 933 patients with ACC and 729,938 with IDC were identified.
Article Synopsis
- The study analyzed gender differences in breast cancer using data from the National Cancer Data Base (NCDB) covering 1998 to 2007, comparing demographics, tumor characteristics, treatments, and outcomes for over 13,000 men and nearly 1.4 million women.
- Men were generally older and had larger tumors, with a higher likelihood of presenting at a more advanced stage compared to women.
- While there were significant differences in overall survival rates—83% for women versus 74% for men—when considering various factors, breast cancer in men and women is ultimately more similar than initially suggested.
Mammographic screening is a proven method for reducing breast cancer mortality for women 40 years of age and older, but the best method for implementation of mammographic screening, particularly in the age group 40-49, remains controversial. The author, in an invited review, summarizes the data and offers guidance based on the best information available for women at risk for breast cancer, and their care providers, with particular emphasis on costs and benefits.
View Article and Find Full Text PDFHypothesis: Body weight correlates with risk of breast cancer death.
Design: A retrospective cohort study using patient medical records, electronic cancer registry data, and archived tissue specimens.
Setting: A 395-bed, comprehensive community hospital.