Publications by authors named "Jon Haitz Badiola"
Polymers (Basel)
October 2022
Article Synopsis
- - Organ-on-chip (OoC) technology aims to replace animal testing in drug discovery, but its use is hindered by slow production and incompatibility with standard lab equipment, along with issues related to the commonly used material, polydimethylsiloxanes (PDMS).
- - This study introduces a new microfluidic device made from cyclic olefin copolymers (COC), which can be mass-produced and used with standard laboratory tools for liver cell culture under dynamic conditions.
- - The COC device successfully cultured HepG2/C3a liver cells for 9 days, displaying good cell proliferation and functionality, demonstrating its potential as an effective OoC platform for liver studies.
