Errors in prostate core biopsy diagnosis in an era of specialisation and double reporting.

Aim: To examine the effects of specialist reporting on error rates in prostate core biopsy diagnosis.

Method: Biopsies were reported by eight specialist uropathologists over 3 years. New cancer diagnoses were double-reported and all biopsies were reviewed for the multidisciplinary team (MDT) meeting.

Contemporary prostate biopsy reporting: insights from a survey of clinicians' use of pathology data.

Aim: To determine how clinicians use data in contemporary prostate biopsy reports.

Methods: A survey was circulated to members of the British Association of Urological Surgeons and the British Uro-oncology Group.

Results: Responses were received from 114 respondents (88 urologists, 26 oncologists).

Death certification: do consultant pathologists do it better?

The completion of the medical certificate of cause of death is required for registration of a death, and this data helps plan healthcare services for the country. Many audits have shown them to be inaccurately completed by junior doctors, but the authors examined whether advice from consultant pathologists could improve this. Using the Office for National Statistics guidelines, the authors found that only 56% of the certificates were appropriately completed.

Error rates in reporting prostatic core biopsies.

Aims: To evaluate the false-negative and false-positive error rates both in a screening and a non-screening population.

Methods And Results: A total of 4192 prostatic biopsies were reported in a 6-year period by 15 consultant histopathologists, two of whom had an interest in uropathology and were deemed to be specialists (J.O.

Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells.

Metastatic cancer cells typically fail to halt migration on contact with non-cancer cells. This invasiveness is in contrast to normal mesenchymal cells that retract on contact with another cell. Why cancer cells are defective in contact inhibition of locomotion is not understood.

Ketamine cystitis as a mimic of carcinoma in situ.

Aims: To describe the histopathological features of a series of patients with ketamine-related cystitis.

Methods And Results: Seventeen patients with ketamine-related cystitis, who had undergone biopsy, were identified and reviewed. Twelve showed ulceration with significant urothelial atypia.

Lichenoid and granulomatous stomatitis: an entity or a non-specific inflammatory process?

Background: The presence of lichenoid or granulomatous inflammation in an oral mucosal biopsy usually suggests a distinct range of diagnostic possibilities. However, the presence of both patterns of inflammation in the same biopsy is uncommon.

Methods: A clinico-pathological study of six patients.