Prophylactic endotracheal intubation in critically ill patients undergoing endoscopy for upper GI hemorrhage.

Background: Cardiopulmonary complications are common after endoscopy for upper GI (UGI) hemorrhage in the intensive care unit (ICU).

Objective: To evaluate the practice and outcome of elective prophylactic endotracheal intubation before endoscopy for UGI hemorrhage in the ICU.

Design: Retrospective, propensity-matched case-control study.

Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease.

Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluated in an attempt to understand this unusual and lethal outcome.

Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients.

Background: Transfusion has long been identified as a risk factor for acute lung injury (ALI)/ARDS. No study has formally evaluated the transfusion of specific blood products as a risk factor for ALI/ARDS in critically ill medical patients.

Method: In this single-center retrospective cohort study, 841 consecutive critically ill patients were studied for the development of ALI/ARDS.