Photodynamic therapy for radiation maculopathy: A case report.

Rationale: The best treatment protocol for radiation maculopathy in children has not been determined. The purpose of this study was to determine the effect of photodynamic therapy (PDT) on radiation maculopathy.

Patient Concerns: An 11-year-old boy who was originally diagnosed with orbital rhabdomyosarcoma when he was 1 year old, in October 2008.

Reproducibility of optic disk evaluation in supine subjects with a Heidelberg Retina Tomograph II laser tomographic scanner.

Aim: The aim of this study was to determine the reproducibility and reliability of optic disk evaluation in supine subjects with a Heidelberg Retina Tomograph II (HRT II).

Methods: One eye was randomly selected for evaluation by HRT II in each of eleven healthy subjects. Five images were obtained by each of two experienced operators at two separate visits with the subjects in both sitting and supine positions.

Intraocular pressure readings obtained through soft contact lenses using four types of tonometer.

Purpose: To compare the reliability and accuracy of intraocular pressure (IOP) measured while wearing soft contact lenses (SCLs) using a non-contact tonometer (NCT), Goldmann applanation tonometer (GAT), iCare rebound tonometer (RBT) and the Tono-Pen XL.

Methods: Twenty-six healthy subjects were examined. The IOP was measured using NCT, GAT, RBT, and the Tono-Pen XL, while the subjects wore SCLs -5.

Ocular surface displacement with and without contact lenses during non-contact tonometry.

Purpose: To evaluate the displacement of the central ocular surface during non-contact tonometry with and without soft contact lenses and determine the factors associated with the displacement of the central ocular surface and intraocular pressure (IOP) reading changes caused by wearing soft contact lenses (CLs).

Methods: One eye each in 21 subjects was studied. The cornea was photographed using a high-speed camera at 5,000 frames/sec during non-contact tonometry without contact lenses (NCL), with -5.

Evaluation of corneal displacement using high-speed photography at the early and late phases of noncontact tonometry.

Purpose: We investigated the extent of corneal displacement and factors associated with the measurement of IOP during the early and late phases of noncontact tonometry.

Methods: One eye in each of 61 healthy volunteers was studied. In each case, the cornea was photographed in profile using a high-speed camera during noncontact tonometry.

Matrix metalloproteinase and cytokine expression in Tenon fibroblasts during scar formation after glaucoma filtration or implant surgery in rats.

Failure of surgery for glaucoma is usually due to post-surgical scarring (fibrosis), a process in which fibroblasts play a prominent role. We investigated the molecular mechanisms of such scarring by examining the expression of matrix metalloproteinases and cytokines in Tenon fibroblasts isolated from rats after glaucoma surgery. Filtration surgery was performed in one eye and implant surgery in the other; and Tenon fibroblasts were isolated from the tissue surrounding the bleb after surgery.

[A case of anterior segment dysgenesis showing change in anterior eye features].

Purpose: Using an ultrasound biomicroscope (UBM) and an endoscope just after birth, We observed the morphological changes in the anterior segment in a case of anterior segment dysgenesis.

Case: The patient was a 9-day-old baby girl born with central opacity and high intraocular pressure. The central cornea was thin and the opacity was ring-shaped.

Corneal displacement during tonometry with a noncontact tonometer.

Purpose: To measure the extent of corneal displacement during the early phase of tonometry using a noncontact tonometer and to determine the factors that affect the extent of the displacement.

Methods: The cornea was photographed in profile by use of a high-speed camera during tonometry with a noncontact tonometer. The frame rate of the camera was 5,000 frames/s.

Intraocular pressure measurement using rebound tonometer for deviated angles and positions in human eyes.

Purpose: To investigate the influence of positional deviations on rebound tonometer measurement of intraocular pressure in humans.

Materials And Methods: Intraocular pressure was measured using the Icare rebound tonometer on the right eyes of 53 subjects in various conditions as follows: first, at a distance of 4, 6, or 8 mm from the center of the cornea with the probe perpendicular to the corneal plane; then, at 2 mm from the limbus in the nasal and temporal regions with the probe perpendicular to the corneal plane or along the visual axis; and lastly, with the angled probe touching the central cornea at angles of 10° or 20°.

Results: Bland-Altman plots between the Goldmann applanation tonometer and rebound tonometer at various conditions revealed 95% limits of agreement ranging from ±4.

Evaluation of rebound tonometer for measuring intraocular pressure at deviated angle and position.

Purpose: To investigate the influence of positional deviations on the rebound tonometer measurement.

Materials And Methods: Ten white rabbits were used. A bottle of balanced salt solution was connected to the anterior chamber, and the IOP was altered by changing the height of the bottle.

Comparison of the prevalence of plateau iris configurations between angle-closure glaucoma and open-angle glaucoma using ultrasound biomicroscopy.

Purpose: To determine the prevalence of plateau iris configurations in acute primary angle-closure (APAC), chronic angle-closure glaucoma (CACG), and open-angle glaucoma (OAG) eyes using ultrasound biomicroscopy.

Materials And Methods: The study included fellow eyes of 27 APAC patients, 26 OAG patients, and 26 CACG patients with no history of APAC. Patients with a history of earlier intraocular surgery or argon laser peripheral iridoplasty were excluded from the study.