Publications by authors named "Johnny Yuk-Yeung Ho"
Cancer Lett
December 2022
Article Synopsis
- TGF-β signaling plays a dual role in cancer, initially identified as a suppressor but increasingly shown to promote tumor growth, particularly within the tumor microenvironment (TME).
- Both cancer and stromal cells produce TGF-β, creating a complex signaling network that influences cancer progression in unexpected ways, revealing both anti-cancer and pro-tumoral effects when disrupted.
- Understanding the molecular mechanisms of TGF-β signaling is crucial for developing targeted cancer treatments that can differentiate between its beneficial and harmful effects.
