Accidental Extravasation of Mitomycin C into the Subcutaneous Tissue.

Introduction: Mitomycin C (MMC) is a common chemotherapeutic agent used to treat a variety of solid tumors. Cutaneous adverse events are rare, but MMC is a known vesicant reported to cause tissue necrosis and sloughing, erythema, and ulceration if incorrectly infused into the subcutaneous tissue. Definitive treatment of extravasation injuries due to MMC depends on the severity of the cutaneous manifestation, which includes stopping the infusion, removing the catheter, or possible debridement.

Catching the GIST: Massive Gastrointestinal Stromal Tumor Presenting as Acute Dyspnea.

We present a case of a 55-year-old woman presenting with worsening shortness of breath and constipation over the course of three days. Initial computed tomography scan showed a large, complex abdominal mass with a vascular pedicle and possible pedunculated origin along the inferior aspect of the greater curvature of the stomach. The mass was further evaluated on magnetic resonance imaging showing an active hemorrhage.

Thyroid Steal Syndrome Secondary to Active Hyperthyroid State.

Thyroid steal syndrome (TSS) is a rare condition characterized by recurrent transient ischemic attack (TIA) that is found to be due to a large thyroid goiter or thyroid hormone derangement causing a diversion of blood flow from the cerebral circulation. Here we report a patient with a history of multiple TIAs thought initially to be due to intracranial arterial stenosis based on CT angiography (CTA) findings, but later found to be secondary to hyperthyroid state causing TSS. To our knowledge, this is the first-ever reported case of TSS secondary to hyperthyroidism and only the second case of TSS secondary to any thyroid hormone derangement.