Publications by authors named "Johnathan Lex"

Article Synopsis
  • This study investigates the relationship between the length of hospital stay (LOS) and the incidence of venous thromboembolism (VTE) in patients undergoing total hip and knee arthroplasties, aiming to create a predictive model using machine learning.
  • Over a 6-year period, data from 498,314 patients showed a decline in VTE rates from 1.11% to 0.76%, which correlated strongly with decreasing LOS.
  • The best predictive model identified significant factors related to VTE risk, suggesting that improved prediction methods could enhance patient monitoring and prevention strategies in arthroplasty cases.
View Article and Find Full Text PDF

Background: Total knee arthroplasty (TKA) is a commonly performed procedure that has traditionally utilized reproducible steps using a set of mechanical instruments. The number of TKAs performed using robotic assistance is increasing, and augmented reality (AR) navigation systems are being developed. Hierarchical task analysis (HTA) aims to describe the steps of a specific task in detail to reduce errors and ensure reproducibility.

View Article and Find Full Text PDF

Background: Previous anterior cruciate ligament (ACL) injury is a risk factor for the development of knee osteoarthritis. Despite advances in ACL reconstruction (ACLR) techniques, many patients with history of ACLR develop end-stage osteoarthritis necessitating total knee arthroplasty (TKA). The purpose of this study was to investigate the impact of prior ACLR on intraoperative and postoperative outcomes of TKA.

View Article and Find Full Text PDF

Background: Periprosthetic infection (PJI) with concomitant extensor mechanism disruption (EMD) and soft-tissue defect-hereinafter termed the "Terrible Triad"-is a devastating complication following total knee arthroplasty. The purpose of this study was to define the surgical and clinical outcomes following management of a cohort of patients who have the Terrible Triad.

Methods: From 2000 to 2022, 127 patients underwent operative management for PJI alone, 25 for PJI with soft-tissue defects (defined as defects requiring flap reconstruction or being a factor contributing to the decision of performing above-knee amputation or arthrodesis), 14 for PJI with EMD, and 22 for the Terrible Triad.

View Article and Find Full Text PDF

Background: The relationship between sex and outcomes, especially complications, after total hip arthroplasty (THA) has not been well established. This study aimed to identify if patient biological sex significantly impacted complications after THA in Ontario, Canada.

Methods: A population-based retrospective cohort study of patients undergoing primary THA in Ontario from April 1, 2015 to March 31, 2020 was conducted.

View Article and Find Full Text PDF

Background: Immigrants and refugees face unique challenges navigating the health care system to manage severe arthritis, because of unfamiliarity, lack of awareness of surgical options, or access. The purpose of this study was to assess total knee arthroplasty (TKA) uptake, surgical outcomes, and hospital utilization among immigrants and refugees compared with Canadian-born patients.

Methods: We included all adults undergoing primary TKA from January 2011 to December 2020 in Ontario.

View Article and Find Full Text PDF
Article Synopsis
  • The study looks at how many patients with knee problems got MRI scans before having knee surgery called total knee arthroplasty (TKA).
  • It found that about 1 in 5 patients had an MRI in the two years before their surgery, and most of these scans were ordered by their regular doctors.
  • The study suggests that getting these MRIs may not be necessary and could be wasting money and making people wait longer for their surgery.
View Article and Find Full Text PDF

Background: Utilization of the direct anterior approach (DAA) for total hip arthroplasty (THA) has risen in popularity. Accurate implant placement is a critical factor that influences patient outcomes. The goal of this study was to compare the accuracy and precision of fluoroscopy with imageless optical navigation in DAA THA.

View Article and Find Full Text PDF

Aims: This study aimed to investigate the risk of postoperative complications in COVID-19-positive patients undergoing common orthopaedic procedures.

Methods: Using the National Surgical Quality Improvement Programme (NSQIP) database, patients who underwent common orthopaedic surgery procedures from 1 January to 31 December 2021 were extracted. Patient preoperative COVID-19 status, demographics, comorbidities, type of surgery, and postoperative complications were analyzed.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to evaluate various computer-assisted navigation platforms for pedicle screw placement by examining factors like accuracy, surgery duration, neurological complications, and blood loss.
  • Stryker showed the highest accuracy for screw placement, while BrainLab had significantly faster operative times compared to Medtronic, with all platforms reducing the risk of major breaches in placement.
  • Overall, the analysis indicates a 60% reduction in major breach risk with computer-assisted navigation versus traditional methods, providing valuable insights for future research and technology procurement.
View Article and Find Full Text PDF

Background: In-office needle arthroscopy (IONA) has been described as a diagnostic alternative to magnetic resonance imaging (MRI) for intra-articular pathology. However, few studies have analyzed its impact on cost and wait times when used as a therapeutic intervention. The purpose of this study was to investigate the impact on cost and wait times associated with offering IONA for partial medial meniscectomy as an alternative to traditional operating room (OR) arthroscopy for patients with irreparable medial meniscus tears on MRI.

View Article and Find Full Text PDF

Purpose: Minimizing complications is an important focus in hip hemiarthroplasty (HHA) for femoral neck fracture (FNF) patients given the associated high morbidity and mortality rates. This systematic review and meta-analysis aimed to compare the clinical and functional outcomes associated with the direct anterior approach (DAA) compared to other surgical approaches used for HHA.

Methods: Studies evaluating HHA-treated FNFs using the DAA were compared through meta-analysis to all other surgical approaches combined and as distinct subgroups.

View Article and Find Full Text PDF

Objective: Immersive virtual reality (IVR) technology is transforming medical education. Our aim was to compare the effectiveness of IVR with cadaveric bone models in teaching skeletal anatomy.

Design: A randomized crossover noninferiority trial was conducted.

View Article and Find Full Text PDF

Background: Over-crowded surgical trays result in perioperative inefficiency and unnecessary costs. While methodologies to reduce the size of surgical trays have been described in the literature, they each have their own drawbacks. In this study, we compared three methods: (1) clinician review (CR), (2) mathematical programming (MP), and (3) a novel hybrid model (HM) based on surveys and cost analysis.

View Article and Find Full Text PDF

Background: There is a growing demand for total joint arthroplasty (TJA) surgery. The applications of machine learning (ML), mathematical optimization, and computer simulation have the potential to improve efficiency of TJA care delivery through outcome prediction and surgical scheduling optimization, easing the burden on health-care systems. The purpose of this study was to evaluate strategies using advances in analytics and computational modeling that may improve planning and the overall efficiency of TJA care.

View Article and Find Full Text PDF

Importance: Artificial intelligence (AI) enables powerful models for establishment of clinical diagnostic and prognostic tools for hip fractures; however the performance and potential impact of these newly developed algorithms are currently unknown.

Objective: To evaluate the performance of AI algorithms designed to diagnose hip fractures on radiographs and predict postoperative clinical outcomes following hip fracture surgery relative to current practices.

Data Sources: A systematic review of the literature was performed using the MEDLINE, Embase, and Cochrane Library databases for all articles published from database inception to January 23, 2023.

View Article and Find Full Text PDF

Introduction: Knee pain is caused by various pathologies, making evaluation in primary-care challenging. Subsequently, an over-reliance on imaging, such as radiographs and MRI exists. Electronic-triage tools represent an innovative solution to this problem.

View Article and Find Full Text PDF

Purpose: To summarize the research on the effectiveness of virtual reality (VR) therapy for the management of phantom limb pain (PLP).

Methods: Three databases (SCOPUS, Ovid Embase, and Ovid MEDLINE) were searched for studies investigating the use of VR therapy for the treatment of PLP. Original research articles fulfilling the following criteria were included: (i) patients 18 years and older; (ii) all etiologies of amputation; (iii) any level of amputation; (iv) use of immersive VR as a treatment modality for PLP; (v) self-reported objective measures of PLP before and after at least one VR session; (vi) written in English.

View Article and Find Full Text PDF

Purpose: The development of augmented reality (AR) technology allows orthopaedic surgeons to incorporate and visualize surgical data, assisting the execution of both routine and complex surgical operations. Uniquely, AR technology allows a surgeon to view the surgical field and superimpose peri-operative imaging, anatomical landmarks, navigation guidance, and more, all in one view without the need for conjugate gaze between multiple screens. The aim of this literature review was to introduce the fundamental requirements for an augmented reality system and to assess the current applications, outcomes, and potential limitations to this technology.

View Article and Find Full Text PDF

Objectives: To determine the impact of dedicated orthopaedic trauma room (DOTR) implementation on operating room efficiency and finances.

Design: Retrospective cost-analysis.

Setting: Single midsized academic-affiliated community hospital in Toronto, Canada.

View Article and Find Full Text PDF

Background: The number of periprosthetic fractures above a total knee arthroplasty continues to increase. These fractures are associated with a high risk of morbidity and mortality. Techniques for addressing these fractures include open reduction internal fixation (ORIF) and revision arthroplasty, including distal femoral replacement (DFR).

View Article and Find Full Text PDF

Background: Total knee arthroplasty (TKA) is one of the most resource-intensive, high-volume surgical procedures. Two drivers of the cost of TKAs are duration of surgery (DOS) and postoperative inpatient length of stay (LOS). The ability to predict TKA DOS and LOS has substantial implications for hospital finances, scheduling, and resource allocation.

View Article and Find Full Text PDF
Article Synopsis
  • - Periprosthetic joint infections (PJI) are serious complications for patients with megaprosthetic implants, leading to higher amputation rates and challenges in treating orthopaedic oncology cases.
  • - The article reviews the mechanisms of bacterial colonization and discusses various anti-bacterial coatings currently being developed or used to combat PJIs, addressing both in vitro outcomes and their clinical significance.
  • - Implementing anti-bacterial coatings on megaprostheses could significantly lower infection rates, enhancing patient outcomes in sarcoma care and major trauma surgeries that require extensive bone reconstruction.
View Article and Find Full Text PDF