Critical analysis of the impact of glottal features in the classification of clinical depression in speech.

The motivation for this work is in an attempt to rectify the current lack of objective tools for clinical analysis of emotional disorders. This study involves the examination of a large breadth of objectively measurable features for use in discriminating depressed speech. Analysis is based on features related to prosodics, the vocal tract, and parameters extracted directly from the glottal waveform.

Three-dimensional fusion of coronary arteries with myocardial perfusion distributions: clinical validation.

Unlabelled: Clinical decisions regarding diagnosis and effective treatment of coronary artery disease frequently require integration of information from various imaging modalities, which are acquired, processed, and read at different physical locations and times. We have developed methods to integrate the information in 2 cardiac imaging studies, perfusion SPECT and coronary angiography. Three-dimensional (3D) models of the coronary artery tree created from biplane angiograms were automatically aligned with 3D models of the left ventricular epicardial surface created from perfusion SPECT.