Publications by authors named "John W Dubay"
Article Synopsis
- Immune checkpoint inhibition therapy has shown promise for improving outcomes in advanced non-small cell lung cancer, but there's a need for better predictive biomarkers; a blood test called host immune classifier (HIC) was evaluated for this purpose in a real-world study.* -
- The INSIGHT study enrolled over 3,570 NSCLC patients and assessed their survival based on HIC designation (HIC-H or HIC-C) and treatment type, revealing that HIC-H patients had significantly longer overall survival compared to HIC-C patients across various treatment regimens, including ICI therapies.* -
- The findings indicate that HIC testing can independently predict patient survival outcomes regardless of the programmed death ligand 1 (PD-L1)
Background: Few studies have examined the real-time and dynamic relationship between lifestyle behaviors and treatment-related symptoms.
Objective: The aim of this study was to examine the associations of daily physical activity and sedentary behavior with symptom burden, pain interference, and fatigue among patients who were undergoing active cancer treatment.
Methods: A total of 22 (mean age = 57 years; 73% women; 55% Black) cancer patients were recruited from a local hospital and reported a daily diary of physical activity, sedentary behavior, symptom burden, pain interference, and fatigue over 10 days.