The development of the C. elegans uterus provides a model for understanding the regulatory pathways that control organogenesis. In C.
View Article and Find Full Text PDFA central question in biology is to understand how gene expression is precisely regulated to give rise to a variety of forms during the process of development. Epigenetic effects such as DNA methylation or histone modification have been increasingly shown to play a critical role in regulation of genome function. GCN5 is a prototypical histone acetyltransferase that participates in regulating developmental gene expression in several metazoan species.
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