Synopsis of recent research by authors named "John S Dennis"
Recent research by John S Dennis focuses on the effects of e-cigarette aerosol components, such as propylene glycol and vegetable glycerin, on mucociliary function and airway inflammation, revealing potential health risks associated with e-cigarette use.
His studies utilize large animal models and primary human bronchial epithelial cells to assess dysfunction in ion channels and the impact of flavorings like menthol on airway clearance mechanisms.
Additionally, his work explores therapies for cystic fibrosis-related airway issues, such as the role of losartan in mitigating inflammation and reducing mucus hypersecretion in both experimental and clinical settings.