Publications by authors named "John Roefaro"
Article Synopsis
- Lecanemab, an amyloid-targeting immunotherapy for Alzheimer’s, shows promise but comes with potential risks for patients.
- An interprofessional team at a medical center developed resources like patient handouts and documentation templates to aid in the infusion process of lecanemab.
- The team plans to share these developed resources and processes with other healthcare settings to improve implementation and monitoring.
Background: Hospital-in-home (HIH) is an innovative model that provides hospital-level care in a patient's home. Pharmacists can enhance the HIH model through medication reconciliation and medication optimization.
Objectives: To integrate a clinical pharmacist into the HIH model and to conduct a formative evaluation of pharmacist contributions, including medication discrepancy resolution, cost savings, and cost avoidance.
The demographics of the Veterans in our care are everchanging, we are currently seeing a major shift in our geriatric Veteran population. World War II (WWII) ended in 1945, meaning that the youngest WWII Veterans are no more than 93 years old. There are currently close to 300,000 WWII Veterans and this number is expected to drop to <50,000 by 2024.
View Article and Find Full Text PDFThe risk of atherosclerotic cardiovascular disease rises with age and remains the leading cause of death in older adults. Evidence for the use of statins for primary prevention in older adults is limited, despite the possibility that this population may derive significant clinical benefit given its increased cardiovascular risk. Until publication of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the Management of Blood Cholesterol, and the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, guidelines for statin prescription in older adults remained unchanged despite new evidence of possible benefit in older adults.
View Article and Find Full Text PDFBackground: Case reports have demonstrated that dual use of cholinesterase inhibitors (ChIs) and urinary anticholinergics (UAChs) in older adults may be associated with delusions, aggression, changes in cognition, and anxiety, which typically resolve on drug discontinuation. Despite opposing mechanisms of action, these drugs continue to be co-prescribed.
Objective: This systematic review evaluates cognitive and functional outcomes of dual use of ChIs and UAChs and describes its prevalence.