Publications by authors named "John Rague"
Article Synopsis
- The study investigates the use of cannabigerol as an indicator of recent cannabis smoking, especially crucial for forensic analysis in incidents like traffic accidents.
- In the study, participants (occasional and daily smokers) were tested for cannabinoids in their blood before and after a supervised smoking session, revealing that cannabigerol levels significantly rose in both groups post-smoking.
- The findings suggest that a detectable level of cannabigerol in blood can accurately indicate recent cannabis use, supporting its potential role in forensic evaluations.
Background: Loperamide, commonly sold under the brand name Imodium® (Johnson & Johnson, Fort Washington, PA), is a widely available, over-the-counter antidiarrheal medication that possesses µ-opioid agonist properties and can have catastrophic cardiac events when misused or abused. Since the start of the opioid epidemic in the United States, there has been an increasing number of case reports and deaths linking loperamide abuse with cardiac events such as torsades de pointes (TdP) and Brugada syndrome.
Case Report: This case report presents a 22-year-old man who presented in cardiac arrest from polymorphic ventricular tachycardia consistent with TdP and a Type 1 Brugada pattern after intentional loperamide abuse.
Introduction: Methylene chloride, also known as dichloromethane, is a volatile hydrocarbon used in paint strippers and removers. Toxicity from methylene chloride may include narcosis and elevated carbon monoxide (CO) levels. Significant injury to the skin can occur after prolonged exposure to methylene chloride and other hydrocarbon-based solvents causing a chemical dermal injury.
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