They tamed the photon: early days of radiation dosimetry.

This article is a tribute to the many physicists who tamed the photon in the service of mankind. Many received Nobel Prizes and other high awards. Several have units named after them.

Immunosuppression in cervical cancer with special reference to arginase activity.

Introduction: Cervical cancer is characterized by an immunosuppressive microenvironment and a Th2-type cytokine profile. Expression of arginase (ASE), the enzyme that converts L-arginine into L-ornithine and urea, is stimulated by Th2-type cytokines.

Objective: To assess the association of ASE activity and L-Arg metabolism products with cervical cancer.

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.

Background: L-arginine is the common substrate for the two isoforms of arginase. Arginase I, highly expressed in the liver and arginase II mainly expressed in the kidney. Arginase I-producing myeloid derived suppressor cells have been shown to inhibit T-cell function by the depletion of L-arginine.

Determination of beta-agonists in liver and retina by liquid chromatography-tandem mass spectrometry.

A liquid chromatography-tandem mass spectrometry (LC/MS/MS) method for the determination of bromobuterol, cimaterol, clenbuterol, clenpenterol, hydroxymethylclenbuterol, isoxsuprine, mabuterol, ractopamine, ritrodrine, salbutamol, terbutaline, and tulobuterol residues in bovine liver and retina is reported. This procedure uses enzymatic digestion, liquid-liquid extraction, and cleanup on Oasis HLB solid-phase extraction cartridges, followed by determination of the residues by LC-tandem quadrupole MS using atmospheric pressure chemical ionization in the positive ion mode. Overall average recoveries ranged from 23 to 76% for liver and 34 to 77% for retina.