Background: Japanese authors first reported a reversible cardiomyopathy due to emotional stress known as Takotsubo cardiomyopathy or stress-induced cardiomyopathy or apical ballooning syndrome. In this case report, we describe Takotsubo cardiomyopathy associated with use of a chemotherapy drug, Regorafenib (Stivarga).
Case History: A 72-year-old female with history of metastatic colon cancer, with liver metastasis status post-resection and a recent diagnosis of primary non-small cell lung cancer on chemotherapy presented with shortness of breath exacerbated on exertion for 3 days.