Publications by authors named "John P Schmitz"

Background There has been increasing concern by the American Dental Association, state dental boards, regional legislators, and specialty groups about the current state of dental anesthesia. Specific interest has surrounded methods to improve patient safety during parental sedation and anesthesia. Many times in the history of dental anesthesia, monitoring advances begin in the hospital for general anesthesia, then downscale, become smaller, and find utility in outpatient anesthesia.

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Following tooth extraction, socket grafts are commonly used to prevent incomplete healing and to optimize the bony site for implant placement (1). Many particulate, composite, and putty-like bone grafting materials either with or without a membrane have been used as socket grafts. This article introduces the layered socket grafting technique for socket grafting without the use of a membrane or primary closure.

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Demineralized bone matrix (DBM) is an osteoconductive and osteoinductive commercial biomaterial and approved medical device used in bone defects with a long track record of clinical use in diverse forms. True to its name and as an acid-extracted organic matrix from human bone sources, DBM retains much of the proteinaceous components native to bone, with small amounts of calcium-based solids, inorganic phosphates and some trace cell debris. Many of DBM's proteinaceous components (e.

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The San Antonio District Dental Society serves approximately 850 dentists in a diverse, 14-county region of southwest Texas. San Antonio is a large metropolitan area, with a major medical center and dental school. The city is also a popular convention destination, regularly hosting the Texas Dental Association and more recently hosting the American Dental Association and the American Association of Dental Schools meetings.

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Prior studies have shown that implant surface roughness affects osteoblast proliferation, differentiation, matrix synthesis, and local factor production. Further, cell response is modulated by systemic factors, such as 1,25(OH)2D3 and estrogen as well as mechanical forces. Based on the fact that peri-implant bone healing occurs in a site containing elevated amounts of prostaglandin E2 (PGE2), the hypothesis of the current study is that PGE2 and arachidonic acid (AA), the substrate used by cyclooxygenase to form PGE2, influence osteoblast response to implant surface roughness.

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Tissue injury and healing.

Oral Maxillofac Surg Clin North Am

August 2005

This article provides a primer on the biochemistry of wound healing for clinical oral and maxillofacial surgeons, recognizing that time frames, tissue growth, and cell types are important factors in the healing process that may influence treatment, whereas the specifics of molecular composition and fiber interaction are less critical at the tissue level. Various injury patterns, including different types of lacerations, blunt and penetrating trauma, blast injuries, and ballistic injuries, are described with an eye toward the ultimate clinical goals of functional and cosmetic reconstruction. As injuries of our incredibly brave military soldiers are studied and treated and their outcomes ultimately assessed, they serve as the models to help us understand changing wound patterns and effects in this new age of terroristic warfare.

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Purpose: The purpose of this study was to use the rat air pouch model of facsimile synovium to evaluate oxidative stress as a primary mechanism in the pathogenesis of degenerative temporomandibular joint (TMJ) disease.

Materials And Methods: Forty-nine Sprague-Dawley adult female rats were used to generate the standard rat air pouch model of facsimile synovium. This was accomplished by daily air injections (20 cc) subdermally through the dorsal skin.

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Purpose: Management of mandibular angle fractures is often challenging and results in the highest complication rate among fractures of the mandible. Optimal treatment for angle fractures remains controversial. Historically, treatment of mandible fractures included intraoperative maxillomandibular fixation (MMF) along with rigid internal fixation.

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Purpose: Adhesion formation in osteoarthritis (OA) of the temporomandibular joint (TMJ) typically results in a sustained limitation of joint movement. We propose the hypothesis that free-radical-mediated crosslinking of proteins underlies this adhesion formation in affected joints. Free radicals may cause oxidative modification of proteins, creating an opportunity for the formation of intramolecular and intermolecular crosslinks via covalent bonds.

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Purpose: The purpose of the present study was to compare the bone-to-screw interface of both AO self-drilling screws (SDSs) and self-tapping screws (STSs) using scanning electron microscopy.

Materials And Methods: The calvaria from Sprague-Dawley rats were harvested, and the periosteum was removed. The samples were stored in saline until use.

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