Publications by authors named "John Mendez"

Chagas disease, a worldwide public health concern, is a chronic infection caused by . Considering chronic persistence correlates with CD4 and CD8 T cell dysfunction and the safety and efficacy profiles of Benznidazol and Nifurtimox, the two drugs currently used for its etiological treatment, are far from ideal, the search of new trypanocidal treatment options is a highly relevant issue. Therefore, the objective of this work was to evaluate the trypanocidal effect and cytokine production induction of three extracts (hexane, dichloromethane and hydroalcoholic) obtained from , a plant traditionally used as a febrifuge in Colombia.

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