Leptospirosis is a significant zoonotic disease prevalent in tropical areas, with severe cases presenting as Weil's syndrome, characterized by jaundice, kidney failure, and bleeding issues; yet, research on liver health in these patients is lacking in Asia.
The study aims to analyze liver biochemical profiles and ultrasound findings in Filipino adults with confirmed leptospirosis and explore their relationship to severe illness outcomes and mortality.
Findings revealed elevated bilirubin levels in leptospirosis patients, but only mild increases in liver enzymes; ultrasound results showed normal liver size and structure, while dyspnea was linked to a higher mortality risk.