Publications by authors named "John M Wolpert"
Article Synopsis
- * Patients who had radical prostatectomy and preoperative MRI scans were analyzed, revealing a significant link between total prostate volume (TPV) and GVPZ, with 40 cc identified as the cutoff for small-to-moderate versus large prostates.
- * Findings suggest that larger BPH prostates may compress the peripheral zone, leading to glandular atrophy, and could potentially offer a protective effect against the growth of PCa, which commonly originates in the peripheral
NRF2 is a redox-sensitive transcription factor that depending on the duration or magnitude of the stress, either translocates to the nucleus (beneficial) or is degraded in the cytosol (harmful). However, the role of NRF2-based mechanism(s) under ethanol (E)-induced developmental toxicity in the placental context remains unknown. Here, we used a rat prenatal model of maternal alcohol stress consisting of intermittent ethanol vapor (IEV) daily from GD11 to GD20 with a 6 h ON/18 h OFF in a vapor chamber and in vitro placental model consisting of HTR-8 trophoblasts exposed to 86 mM of E for either 24 h or 48 h.
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