Non-hyperaemic pressure ratios to guide percutaneous coronary intervention.

The use of fractional flow reserve (FFR) in guiding revascularisation improves patient outcomes and has been well-established in clinical guidelines. Despite this, the uptake of FFR has been limited, likely attributable to the perceived increase in procedural time and use of hyperaemic agents that can cause patient discomfort. This has led to the development of instantaneous wave-free ratio (iFR), an alternative non-hyperaemic pressure ratio (NHPR).

Physical activity in survivors of childhood acute lymphoblastic leukaemia.

Aim: To objectively measure levels of physical activity in children, following treatment for acute lymphoblastic leukaemia (ALL).

Methods: Nineteen children who had completed treatment for ALL 6 months-5 years prior to study enrollment wore an accelerometer for 2 weekdays and 2 weekend days.

Results: The children spent an average of 141 +/- 74 min/day engaged in moderate to vigorous physical activity (MVPA), an amount similar to that previously documented in healthy children.