Evolution of coronary artery calcification in patients with chronic kidney disease Stages 3 and 4, with and without diabetes.

Background: The purpose of this study was to report the evolution of coronary artery calcification (CAC) in subjects with chronic kidney disease Stages 3 and 4 comparing those with and without diabetes. We previously reported prevalence in the same population.

Methods: CAC was measured using multi-slice computer tomography.

Longitudinal changes of insulin-like growth factors and their binding proteins throughout normal pregnancy.

Background: Insulin-like growth factors (IGFs) are anabolic proteins that are essential regulators of cell division, differentiation and growth. We describe the longitudinal changes in IGF-I, IGF-II and the binding proteins IGFBP-1, -2 and -3 before and during normal pregnancy.

Method: Serum samples were taken before conception and then at 12, 24 and 36 weeks of gestation in 41 healthy women with uncomplicated pregnancies.