Publications by authors named "John M Gonzalez"

Elective undergraduate courses are offered at the University of Georgia and the University of Florida that explore veterinary careers, offer guidance on being a successful veterinary school applicant, and expose students to the reality of the profession through guest speakers. Students ( = 276) from both universities responded to a survey offered at the first and last class period over the course of five semesters. Using 100-point Likert scales, students were asked to gauge their opinion of and interest in the profession and demonstrate their confidence in various aspects of building a successful application.

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The objective of this study was to determine the daily dietary nicotinamide riboside (NR) dose required to maximize the delay of subjective muscle fatigue onset. Barrows ( = 100) were assigned to one of five treatments: a conventional swine finishing diet containing 0 (CON), 15 (15NR), 30 (30NR), 45 (45NR) mg·kg body weight·d NR, or CON supplemented with 45 mg·kg body weight·d NR by drench or cookie dough (DRE). All treatments were administered for the final 11 days of feeding.

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The National Beef Quality Audit - 2022 serves as a benchmark of the current fed steer and heifer population of the U.S. beef industry and allows comparison to previous audits as a method of monitoring industry progress.

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The objective of this study was to examine the effects of nicotinamide riboside (NR) feeding on high-yield broiler growth and meat quality. Fertilized Cobb 700 by-product eggs ( = 3,240) were randomly assigned to one of four in ovo treatments and injected with 0 (), 250 (), 500 (), or 1,000 () mM NR at incubation-day 10. Chicks were hatched, vent sexed, and randomly placed 18 per pen in one of 32 floor pens.

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The National Beef Quality Audit (NBQA)-2022 serves as a benchmark of the current market cow and bull sectors of the U.S. beef industry and allows comparison to previous audits as a method of monitoring industry progress.

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Chagas disease is a parasitic infection caused by the protozoan . One of the complications of the disease is the infection of the central nervous system (CNS), as it can result from either the acute phase or by reactivation during the chronic phase, exhibiting high mortality in immunocompromised patients. This systematic review aimed to determine clinical and paraclinical characteristics of patients with Chagas disease in the CNS.

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Article Synopsis
  • The study investigates how the immune responses (antibodies and CD4 T cells) to SARS-CoV-2 from natural infection and vaccination change over time, focusing on variants like Mu, Gamma, and Delta.
  • It found that antibody levels decline after 6 months, particularly in mildly infected individuals, while those severely infected maintain higher levels; vaccination boosts antibody production but they also decrease over time.
  • The cross-recognition of variants showed varying effectiveness, and prior exposure to the virus influenced the immune response, suggesting important considerations for future vaccine development against emerging variants.
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Canine core vaccine titer screenings are becoming increasingly popular in veterinary practice as a tool to guide vaccination decisions, despite a lack of supportive, peer-reviewed evidence-based literature. Additionally, it has been suggested that the canine core vaccine duration of host protective immunity can persist past the currently recommended vaccination interval. Thus, this study evaluated serum antibody titers against three core antigens in dogs with known vaccination histories and lifestyles, analyzing the effect of life stage, exposure risk, and time since last vaccination (TSLV).

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Trypanosoma cruzi is the etiological agent of Chagas disease, an important cause of infectious chronic myocardiopathy in Latin America. The life cycle of the parasite involves two main hosts: a triatomine (arthropod hematophagous vector) and a mammal. Epimastigotes are flagellated forms inside the triatomine gut; they mature in its intestine into metacyclic trypomastigotes, the infective form for humans.

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, the causal agent of Chagas disease, has coexisted with humans for thousands of years. Therefore, the parasite has developed several mechanisms of antigenic variability that has allowed it to live inside the cells and evade the host immune response. Since  displays an intracellular cycle-stage, our research team focused on providing insights into the CD8 T cells immune response in chronic Chagas cardiomyopathy.

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Objective: To determine whether prepandemic sera from patients with Chagas disease recognise SARS-CoV-2 antigens.

Materials And Methods: Forty sera from patients with Chagas disease were tested for the presence of IgG cross-reactivity against the nucleocapsid protein (NP) and spike (S) SARS-CoV-2 proteins by ELISA. Positive samples were tested again using a different ELISA and CLIA, both against NP.

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Article Synopsis
  • - The study investigated the effectiveness of using closed face shields along with surgical masks to reduce the transmission of COVID-19 (SARS-CoV-2) among working adults in Bogotá, Colombia during the pandemic.
  • - Participants were randomly divided into two groups: one wore closed face shields with surgical masks while the other group wore only surgical masks, and the primary outcome assessed was the rate of positive COVID-19 test results over a follow-up period of 21 days.
  • - Results showed that the closed face shield plus surgical mask combination was not less effective than using just a surgical mask, with very low rates of infection in both groups, suggesting that this method could be suitable for high-risk settings.
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Background: Characterized by an inflammatory pathogenesis, acne is the most common skin disorder worldwide. Altered sebum production, abnormal proliferation of keratinocytes, and microbiota dysbiosis represented by disbalance in population structure, have a synergic effect on inflammation of acne-compromised skin. Although the role of as a single factor in acne development is still under debate, it is known that skin and skin-resident immune cells recognize this bacterium and produce inflammatory markers as a result.

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The objective of this study was to determine the effects of in ovo injection of high-yield broiler embryos with nicotinamide riboside (NR) on pectoralis major muscle (PMM) development, growth, and gene expression. Fertilized Cobb 700 broiler eggs were randomly assigned to one of four treatments within a 2 × 2 factorial design. Factor 1 consisted of NR dose (DOS) with eggs receiving 0 or 2.

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Continued waves, new variants, and limited vaccine deployment mean that SARS-CoV-2 tests remain vital to constrain the coronavirus disease 2019 (COVID-19) pandemic. Affordable, point-of-care (PoC) tests allow rapid screening in non-medical settings. Reverse-transcription loop-mediated isothermal amplification (RT-LAMP) is an appealing approach.

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Chagas disease (ChD) is a chronic infection caused by . This highly diverse intracellular parasite is classified into seven genotypes or discrete typing units (DTUs) and they overlap in geographic ranges, vectors, and clinical characteristics. Although studies have suggested that ChD progression is due to a decline in the immune response quality, a direct relationship between T cell responses and disease outcome is still unclear.

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Within the past three decades, red meat and poultry scientists focused on developing strategies and technologies to manipulate muscle development during embryonic and fetal development. This area continues to be an area of focus because muscle fiber number is established during this time and determines the basis for all future growth. In poultry, numerous studies demonstrated in ovo feeding of growth factors, vitamins, or other nutrients improved chick embryonic muscle and intestinal development.

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The objective of this study was to determine effects of extended aging and intramuscular location on Warner-Bratzler shear force (WBSF), muscle fiber cross-sectional area (CSA), and protein degradation of semitendinosus (ST) and longissimus lumborum (LL) steaks. Left ST and LL were removed from 40 carcasses at 6 d postmortem. The ST was fabricated into five locations (LOC), with LOC 1 being most proximal and LOC 5 being most distal.

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Egg production is an important economic trait in the commercial poultry industry. Ovarian follicle development plays a pivotal role in regulation of laying hen performance and reproductive physiology. However, the key genes and signaling pathways involved in the various-stages of laying hen follicular development remain poorly understood.

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The objective of this study was to determine the effects of in ovo injection of nicotinamide riboside (NR) on broiler embryonic myogenesis. Fertilized Cobb 500 broiler eggs (N = 240) were sorted by weight and within each strata, randomly assigned to 1 of 4 NR dose treatments (0 mmol, 250 mmol, 500 mmol, or 1 mol; final concentration in yolk of 0, 2.5, 5.

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The objective of this study was to collect and interpret three-axis acceleration, temperature, and relative humidity data from six locations within commercial transport trailers shipping market-weight pigs. Transport was observed in Kansas (n = 15) and North Carolina (n = 20). Prior to loading, three-axis accelerometers were affixed to six locations on the trailers: top fore (TF), top center (TC), top aft (TA), bottom fore (BF), bottom center (BC), and bottom aft (BA) compartments.

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Article Synopsis
  • - Celiac disease (CD) is an autoimmune disorder triggered by gluten in genetically predisposed individuals, with a global prevalence of around 1.4%, but limited studies have been done in Latin American populations like Colombia.
  • - This study aimed to assess CD marker prevalence in 228 Colombian blood donors, using tests for specific antibodies (IgA anti-TTG and anti-EMA) and checking for genetic markers (HLA-DQ2 and HLA-DQ8).
  • - The results indicated a 1.32% prevalence of positive CD markers and a higher percentage of European and Native American genetic ancestry among those testing positive, suggesting a notable presence of CD in Colombia compared to prior studies.
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Abnormal collagen infiltration in the , breast muscle, of fast-growing big broilers has led to woody breast (WB) myopathy resulting in meat quality issues. Mechanisms to degrade the collagen were investigated to potentially improve WB texture. Freshly deboned WB fillets ( = 5 per trial; 3 trials) were ground and divided in to 25 g portions.

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