Anatomical correlates of blepharospasm.

Background: Focal dystonia is a neurological disorder characterized by unwanted muscle spasms. Blepharospasm is a focal dystonia producing an involuntary closure of the eyelid. Its etiology is unknown.

A magnetization transfer imaging study of corpus callosum myelination in young children with autism.

Background: Several lines of evidence suggest that autism may be associated with abnormalities in white matter development. However, inconsistencies remain in the literature regarding the nature and extent of these abnormalities, partly because of the limited types of measurements that have been used. Here, we used magnetization transfer imaging to provide insight into the myelination of the corpus callosum in children with autism.

Comparison of methods for obtaining longitudinal whole-brain magnetization transfer measurements.

Purpose: To investigate whether the method of applying image masks can alter quantifiable measures determined from whole-brain MTR calculations.

Materials And Methods: Thirty-five T1/MT image pairs were obtained from five normal volunteers. For each pair a mask was used to specify the regions to be analyzed.