Publications by authors named "John L Lederer"
Article Synopsis
- The study aimed to evaluate how effective the SpaceOAR hydrogel is in reducing radiation proctitis when combined with prostate brachytherapy in a group of 731 patients.
- Among patients using the hydrogel, the incidence of radiation proctitis was significantly lower (4.1%) compared to those not using it (12.2%), with specific rates showing even greater reductions in different treatment scenarios.
- The findings suggest that SOAR not only reduces the occurrence of radiation proctitis but also highlights the need for more research to understand inflammation patterns observed during treatment.
Objectives: The aim of the present study was to report on our early experience with hydrogel spacer (SpaceOAR) placement in combination with iodine-125 low-dose-rate brachytherapy for prostate cancer.
Methods: From April 2018, SpaceOAR hydrogel spacer was placed in 100 consecutive patients undergoing iodine-125 low-dose-rate brachytherapy. Complications and the status of the placement were evaluated.
Background: Our aim was to report clinical and biochemical outcomes of transperineal interstitial permanent prostate brachytherapy in the treatment of Japanese patients with clinically organ-confined prostate cancer in Hawaii.
Methods: Ninety-five Japanese patients underwent transperineal interstitial permanent prostate brachytherapy using either iodine-125 or palladium-103 for clinical T1c-T2b N0 M0 prostate cancer. These procedures were carried out between December 1998 and December 2002 at The Queen's Medical Center in Honolulu, Hawaii.
Purpose: We described the temporarily increase phenomenon in prostate-specific antigen level (PSA bounce) after transperineal interstitial permanent prostate brachytherapy (TIPPB) for localized prostate cancer.
Materials And Methods: From December 1998 to May 2003, 500 consecutive patients with localized prostate cancer were treated with TIPPB using iodine-125 or palladium-103. We examined 200 patients who have more than 2-year PSA follow-up.