Treatment of patch and plaque stage mycosis fungoides with imiquimod 5% cream.

Background: Systemic interferon is effective in the treatment of mycosis fungoides (MF). Imiquimod is effective in the treatment of some epidermal neoplasms and induces localized interferon production.

Objective: To evaluate the safety and efficacy of topical imiquimod 5% cream for the treatment of patch and plaque stage MF.